Evidence map›Paper›PMID 41246125›Full record

ArticleLaryngoscope investigative otolaryngology2025

Pollen Exposure and Chronic Rhinosinusitis Quality of Life Disease Severity.

Benton Tullis, Jess C Mace, Conner Massey, Stuart Batterman, Vijay R Ramakrishnan, Daniel M Beswick, Zachary M Soler, Timothy L Smith, Jeremiah A Alt, Amarbir S Gill

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02720653 (Determinants of Olfactory Dysfunction in Chronic Rhinosinusitis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02720653 unknown statusnot on this map

Determinants of Olfactory Dysfunction in Chronic Rhinosinusitis

TypeobservationalSponsorOregon Health and Science UniversityRan2016 to 2022Enrolled418ConditionsChronic Rhinosinusitis, Olfactory DysfunctionArmsEndoscopic sinus surgery
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Benton TullisDepartment of Otolaryngology - Head and Neck Surgery University of Utah Salt Lake City Utah USA.ORCID https://orcid.org/0000-0003-4744-8550
Jess C MaceDivision of Rhinology and Sinus Surgery/Oregon Sinus Center, Department of Otolaryngology - Head and Neck Surgery Oregon Health & Science University (OHSU) Portland Oregon USA.
Conner MasseyDepartment of Otolaryngology - Head and Neck Surgery University of Colorado School of Medicine Aurora Colorado USA.
Stuart BattermanDepartment of Environmental Health Sciences, School of Public Health University of Michigan Ann Arbor Michigan USA.
Vijay R RamakrishnanDepartment of Otolaryngology - Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.
Daniel M BeswickDepartment of Otolaryngology - Head and Neck Surgery University of California Los Angeles California USA.ORCID https://orcid.org/0000-0003-1898-0417
Zachary M SolerDepartment of Otolaryngology -Head and Neck Surgery Medical University of South Carolina Charleston South Carolina USA.ORCID https://orcid.org/0000-0002-4304-595X
Timothy L SmithDivision of Rhinology and Sinus Surgery/Oregon Sinus Center, Department of Otolaryngology - Head and Neck Surgery Oregon Health & Science University (OHSU) Portland Oregon USA.ORCID https://orcid.org/0000-0002-6424-7083
Jeremiah A AltDepartment of Otolaryngology - Head and Neck Surgery University of Utah Salt Lake City Utah USA.ORCID https://orcid.org/0000-0003-0560-5028
Amarbir S GillDepartment of Otolaryngology - Head and Neck Surgery University of Michigan Ann Arbor Michigan USA.

Funding

Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
DETERMINANTS OF SURGICAL OUTCOMES IN CHRONIC SINUSITISR01DC005805 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SMITH, TIMOTHY L, SOLER, ZACHARY M · 2004 to 2020
$7.6M
NIDCD NIH HHS R01 DC005805NIEHS NIH HHS P30 ES017885
6 · The paper itself

Abstract

Background: Environmental factors, such as air irritants, may play an important role in chronic rhinosinusitis (CRS); however, no studies to date have examined the role of pollen in CRS disease severity. Here, we analyze the effects of pollen exposure on disease-specific and general quality-of-life (QOL) reports. Methods: Patients were enrolled prospectively across four academic medical centers and completed the 22-item SinoNasal Outcome Test (SNOT-22) and Medical Outcomes Study Questionnaire Short-Form 6-D (SF-6D) surveys at enrollment. Mean annual pollen exposure over a 5-year period before enrollment was obtained from the National Allergy Bureau using residence zip codes. Unadjusted Spearman's correlation coefficients ( Results: One hundred and three patients were included and 55% had a history of allergy. Higher 5-year mean ragweed pollen exposure correlated with worse presenting SNOT-22 ( Conclusion: This multi-institutional pilot study suggests that weed and ragweed pollen may negatively impact the QOL of patients with CRS, but further studies are needed to confirm these findings. Level of Evidence: 3. Trial Registration: Clinical trial registration ID: NCT02720653 (www.clinicaltrials.gov).

Indexed as

chronic rhinosinusitisendoscopic sinus surgeryenvironmentmulti‐institutionparticulate matterpollenpreoperative exposurequality of lifeSNOT‐22surgical outcomes

Identifiers

PMID41246125
PMCPMC12612688

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.