Evidence map›Paper›PMID 41246118›Full record

ArticleTouchREVIEWS in endocrinology2025

Metabolic Syndrome in Older Adults: When Function Trumps Numbers.

Marcio José Concepción-Zavaleta, Eduardo Cabellos-Acuña, Jenyfer Maria Fuentes-Mendoza, José Paz-Ibarra

Abstract readEditorial
In one paragraph

Article in TouchREVIEWS in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marcio José Concepción-ZavaletaSchool of Medicine, Universidad Científica del Sur, Lima, Peru.
Eduardo Cabellos-AcuñaDepartment of Geriatrics, Hospital de Emergencias Villa El Salvador, Lima, Peru.
Jenyfer Maria Fuentes-MendozaSchool of Medicine, Universidad Científica del Sur, Lima, Peru.
José Paz-IbarraDepartment of Endocrinology, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This editorial critiques the limitations of traditional metabolic syndrome criteria in older adults, arguing that age-related changes in body composition, vascular stiffness and frailty render standard thresholds inadequate. Highlighting the 'obesity paradox' and risks of intensive blood pressure/lipid control, the article advocates for a frailty-centred approach integrating functional status, body composition (e.g. dual-energy X-ray absorptiometry) and inflammation markers over rigid numerical targets. Practical strategies include sarcopenia screening (SARC-F), resistance training and individualized glycaemic/blood pressure goals to avoid overtreatment in frail patients. The paradigm shift aims to improve risk stratification and align care with geriatric priorities.

Indexed as

Ageingfrailtyhyperglycaemiahypertensionmetabolic syndromeobesitysarcopenia

Identifiers

PMID41246118
PMCPMC12616668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.