ArticleFrontiers in cardiovascular medicine2025
Impact of catheter-directed thrombolysis access approach on entire-limb deep vein thrombosis: a focus on inflow patency.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This retrospective study aimed to evaluate the influence of inflow (femoropopliteal) patency on the efficacy of catheter-directed thrombolysis (CDT) in treating entire-limb deep venous thrombosis (DVT). Methods: From January 2018 to December 2022, 121 individuals diagnosed with acute entire-limb DVT were treated with CDT. CDT was performed through the ipsilateral popliteal vein (AGA) or the contralateral common femoral vein (RGA). Baseline characteristics and segmental patency were compared between the two access approaches groups. The severity of post-thrombotic syndrome (PTS) was compared between different inflow patency groups. Propensity-score matching (PSM) was used to balance confounding factors. Potential risk factors for PTS were analyzed using univariate and multivariate regression analysis. Results: Thirty-four patients received the AGA approach, while 87 individuals were treated with the RGA approach. The AGA group had superior patency compared to the RGA group in both the popliteal and femoral veins ( Conclusion: "Good" inflow patency decreased the incidence and degree of PTS among patients with entire-limb DVT.
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