Evidence map›Paper›PMID 41246013›Full record

ArticleFrontiers in cardiovascular medicine2025

Exploring challenges to medication adherence aacmong young and middle-aged adults with coronary heart disease in China: a qualitative study.

Jianli Guo, Jian Ma, Mengqi Xu, Xiaoli Huang, Yuan Ding, Lingyan Zhu, Wengui Zheng

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianli GuoDepartment of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jian MaDepartment of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Mengqi XuThe Nethersole school of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Xiaoli HuangDepartment of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan DingDepartment of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lingyan ZhuDepartment of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wengui ZhengDepartment of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although coronary heart disease (CHD) is becoming increasingly common among young and middle-aged adults, their outcomes usually remain suboptimal. One major contributing factor is poor medication adherence. This study aims to explore the challenges they face in maintaining adherence to prescribed medications. Methods: This was a qualitative study. 27 young and middle-aged adults with CHD (20 men and 7 women) were recruited from a tertiary general hospital in Shanghai between March and May of 2025. Data were collected through semi-structured interviews. An inductive thematic analysis approach was used for data analysis. Results: Two themes and four sub-themes were identified in total: (1) Struggling with Illness Identity and Long-Term Medication: Viewing CHD as an acute condition; Suffering from social isolation due to CHD. (2) Taking Medication as an Intruder in Life: Disrupting daily routines due to medications; Experiencing conflicts between medication taking and social responsibility. Conclusion: Young and middle-aged adults with CHD may have difficulty maintaining medication adherence due to distorted illness perceptions, emotional resistance to accepting a chronic condition, and the marginalization of medication-taking within their busy daily routines. These findings highlight the need to explore psychological approaches, such as Acceptance and Commitment Therapy (ACT), as potentially relevant strategies to support illness acceptance and psychological adjustment in this demographic. In addition, nurse-led initiatives that facilitate the integration of medication-taking into daily life warrant further investigation. Future mixed-methods and interventional studies are needed to test the feasibility and effectiveness of these approaches.

Indexed as

coronary heart diseasemedication adherencequalitative studysecondary preventionyoung and middle-aged

Identifiers

PMID41246013
PMCPMC12611870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.