Evidence map›Paper›PMID 41245946›Full record

ArticleHealth science reports2025

Urgent Need to Focus on Gender-Diverse Adolescents in Mental Health Prevention Research: A Cross-Sectional Comparative Study.

Sabrina Mittermeier, Sarah Franke, Linda M Bonnekoh, Georg Romer, Marcel Romanos, Nikolaus Kleindienst, Arne Buerger

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sabrina MittermeierDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health University Hospital of Wuerzburg Wuerzburg Germany.ORCID https://orcid.org/0009-0007-5245-0686
Sarah FrankeDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health University Hospital of Wuerzburg Wuerzburg Germany.
Linda M BonnekohDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University of Muenster Muenster Germany.
Georg RomerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University of Muenster Muenster Germany.
Marcel RomanosDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health University Hospital of Wuerzburg Wuerzburg Germany.
Nikolaus KleindienstInstitute of Psychosomatic Medicine and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health Mannheim Heidelberg University Heidelberg Germany.
Arne BuergerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health University Hospital of Wuerzburg Wuerzburg Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Gender-diverse adolescents-those whose gender identity differs from their assigned sex at birth or who do not conform to traditional binary gender norms-are at significantly higher risk for mental health issues, including suicidality and non-suicidal self-injury (NSSI). However, most prevention efforts remain focused on cisgender youth. This study aims to directly compare levels of emotional dysregulation, depressive symptoms, suicidality, and NSSI between gender-diverse adolescents and their cisgender peers to inform gender-sensitive prevention strategies. Methods: This cross-sectional analysis was conducted in a school-based sample with participants aged 8-15 years. Gender identity was self-reported through self-categorization using a single item with three response options (female, male, diverse). Emotional dysregulation (DERS-SF), depressive symptoms (PHQ-9), suicidality (PSS), and NSSI (DSHI-9) were assessed. Group comparisons between gender-diverse adolescents ( Results: Compared to female-identifying and male-identifying adolescents, gender-diverse adolescents showed significantly higher emotional dysregulation (vs. females: Conclusion: Gender-diverse adolescents exhibit substantially higher levels of emotional and behavioral distress compared to both female-identifying and male-identifying adolescents. These findings highlight the urgent need for inclusive mental health screening and targeted prevention programs that address the distinct psychological profiles and elevated risks within gender-diverse youth populations.

Indexed as

adolescenceemotional dysregulationgender diversepreventionsuicidality

Identifiers

PMID41245946
PMCPMC12611714

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.