ArticleFrontiers in neurology2025
Hypothesis paper: high prevalence of Tinel sign in hypermobile Ehlers-Danlos syndrome.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Ehlers-Danlos syndromes (EDS) encompass a group of genetic connective tissue disorders that affect the structure and function of proteins and enzymes that provide stability to the body. The hypermobile subtype of EDS (hEDS) is the most common and is characterized by joint hypermobility, skin hyperextensibility, and widespread musculoskeletal pain. Neuropathic symptoms, including pain, numbness, tingling, and weakness, are increasingly recognized in this population. This paper proposes a study to test the hypothesis that hEDS individuals will have a higher prevalence of positive Tinel signs compared to controls, indicating heightened sensitivity to nerve irritation or compression in hEDS that can guide better diagnosis and treatment.
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