Evidence map›Paper›PMID 41245852›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2025

Candidiasis epidemiology and outcomes including emergence of

Ricky Huynh-Phan, Ardath Plauche, William L Musick, Kady Phe, Wesley J Hoffman, Mayar Al Mohajer, Todd Lasco, Nicholas D Beyda, Taryn A Eubank, Kevin W Garey

Abstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ricky Huynh-PhanUniversity of Houston College of Pharmacy, Houston, TX, USA.
Ardath PlaucheMemorial Hermann Health System, Houston, TX, USA.ORCID https://orcid.org/0000-0002-9058-2395
William L MusickHouston Methodist Hospital, Houston, TX, USA.ORCID https://orcid.org/0000-0002-5148-4290
Kady PheBaylor St. Luke's Medical Center, Houston, TX, USA.
Wesley J HoffmanHouston Methodist Hospital, Houston, TX, USA.ORCID https://orcid.org/0000-0002-1180-021X
Mayar Al MohajerBaylor St. Luke's Medical Center, Houston, TX, USA.
Todd LascoBaylor St. Luke's Medical Center, Houston, TX, USA.
Nicholas D BeydaUniversity of Houston College of Pharmacy, Houston, TX, USA.ORCID https://orcid.org/0000-0002-9999-1478
Taryn A EubankUniversity of Houston College of Pharmacy, Houston, TX, USA.ORCID https://orcid.org/0000-0002-6645-406X
Kevin W GareyUniversity of Houston College of Pharmacy, Houston, TX, USA.ORCID https://orcid.org/0000-0003-2063-7503

Funding

Project 3: Functional Microbiome and Host Signatures in Transition from Commensal to pathogenP01AI152999 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SAVIDGE, TOR C. · 2020 to 2025
$12.0M
VENOUS: A translational study of enterococcal bacteremiaR01AI148342 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ARIAS, CESAR AUGUSTO · 2020 to 2024
$3.9M
Clinical Impact of the Cefazolin Inoculum EffectR01AI173138 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI Cesar Augusto Arias · 2023 to 2026
$2.6M
POR Program on Genomic Prediction of Antimicrobial Resistance in VREK24AI121296 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ARIAS, CESAR AUGUSTO · 2016 to 2025
$1.5M
Texas Medical Center Training Program in Antimicrobial ResistanceT32AI141349 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GARSIN, DANIELLE A · 2019 to 2023
$1.3M
NIAID NIH HHS K24 AI121296NIAID NIH HHS P01 AI152999NIAID NIH HHS R01 AI148342NIAID NIH HHS R01 AI173138NIAID NIH HHS T32 AI141349
6 · The paper itself

Abstract

Background: Invasive candidiasis including candidemia is a common healthcare-associated infections with significant morbidity and mortality. The USA does not have mandatory national surveillance for mucocutaneous or invasive candidiasis which complicates estimation of epidemiology and outcomes. The aim of this project was to describe the epidemiology, mortality, and Methods: This secondary database analysis used clinical microbiology data from adults hospitalized at three large health systems (25-hospitals) in the Greater Houston area totaling over 1.6 million hospitalization days per year from 2018 to 2023. Proportion and rates of Candida cultures per 10,000 hospitalization days were calculated. Risk factors for mortality and Results: Within the study period, 7514 hospitalized patients aged 64 ± 16 years (mean± standard deviation (SD)) with 10,183 unique Conclusion: These analyses highlight the significant burden of candidiasis and the emergence of new strains, including

Identifiers

PMID41245852
PMCPMC12616563

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.