Evidence map›Paper›PMID 41245847›Full record

ReviewAntimicrobial stewardship & healthcare epidemiology : ASHE2025

A research agenda for burn infection prevention: identifying knowledge gaps and prioritizing future directions.

Madhuri M Sopirala, David Weber, Geeta Sood, Mohamed Yassin, Tina L Palmieri, Supriya Narasimhan, Clifford Sheckter, Julie Caffrey, Samuel Mandell, Larissa Pisney and 9 more

Abstract readReview
In one paragraph

Review in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Madhuri M SopiralaDivision of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID https://orcid.org/0000-0003-0613-1741
David WeberDivision of Infectious Diseases, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Geeta SoodDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Mohamed YassinUniversity of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0002-6489-3499
Tina L PalmieriBurn Division, Department of Surgery, University of California, Davis and Shriners Children's Northern California, Sacramento, CA, USA.
Supriya NarasimhanDepartment of Medicine, Santa Clara Valley Medical Center, San Jose, CA, USA.ORCID https://orcid.org/0000-0002-4996-3479
Clifford SheckterDepartment of Surgery, Santa Clara Valley Medical Center, San Jose, CA, USA.
Julie CaffreyBayview Burn Center, Department of Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD, USA.
Samuel MandellDepartment of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Larissa PisneyDivision of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO, USA.
Sheetal KandiahDivision of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Jyoti SomaniInfection Prevention and Control Program, Jackson Health System, Miami, FL, USA.
Natalie MackowDivision of Infectious Diseases, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.ORCID https://orcid.org/0000-0001-7212-3833
Karen BrustUniversity of Iowa Health Care, Iowa City, IA, USA.ORCID https://orcid.org/0000-0001-5853-2323
Sara KarabaDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0001-8452-5549
Michelle DollVCU School of Medicine, Richmond, VA, USA.ORCID https://orcid.org/0000-0003-2477-1240
Donald ChenDivision of Infectious Diseases; Infection Prevention, Westchester Medical Center, Valhalla, NY, USA.
Lilian AbboInfection Prevention and Control Program, Jackson Health System, Miami, FL, USA.
Werner BischoffSection of Infectious Diseases, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.ORCID https://orcid.org/0000-0003-1388-3642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Burn injuries result in loss of skin barrier and altered immune responses that in turn make patients especially vulnerable to healthcare-associated infections. Despite prolonged exposures of these patients to hospital environments, burn-specific infection prevention strategies are understudied. We present a research agenda identifying key research gaps and organizing them into priority areas to guide future investigations in this high-risk population. Design: Members of the Society for Healthcare Epidemiology of America (SHEA) Burn Infection Prevention and Control Special Interest Group and the American Burn Association (ABA) collaborated to develop this research agenda, combining expertise in infection prevention, antimicrobial stewardship, and burn care. Results: We identified five priority areas: (1) improving surveillance and epidemiologic data on burn infections; (2) better understanding of microbiology, including biofilms and the microbiome; (3) evaluating wound healing strategies; (4) refining infection prevention and control practices unique to burn units; and (5) building burn patient specific risk assessment and predictive models. The agenda highlights the need for standardized definitions and shared data platforms. It calls for evaluation of practical strategies for infection prevention, stewardship, and environmental control. Conclusions: This research agenda intends to help guide future studies aimed at furthering knowledge and improving outcomes in burn care.

Identifiers

PMID41245847
PMCPMC12616570

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.