ArticleJournal of experimental orthopaedics2025
Tourniquet effect on cement penetration in total knee arthroplasty: A systematic review and meta-analysis.
Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A Commentary on "Impact of preoperative frailty on venous thromboembolism risk following total hip and knee arthroplasty: a meta-analysis".International journal of surgery (London, England) · 2026Article
- Tourniquet effect on cement penetration in total knee arthroplasty: A systematic review and meta-analysis.Journal of experimental orthopaedics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Total knee arthroplasty (TKA) is a standard orthopaedic procedure for severe knee arthritis, often resulting in high patient satisfaction. However, complications, such as aseptic loosening, remain a significant concern, some thought to be linked to insufficient cement penetration. Using a tourniquet during surgery to improve cement penetration is a topic of debate, with evidence regarding its mixed effectiveness. This review aims to evaluate the impact of tourniquet application on cement penetration, TKA outcomes and related complications. Methods: A meta-analysis adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was conducted, analyzing comparative studies from PubMed, Scopus, Web of Science and Embase. Eligibility criteria focused on studies assessing tourniquet effects on cement penetration, complications and other surgical outcomes. Data extraction and quality assessment followed standardized protocols. Statistical analyses employed a random-effects model to account for heterogeneity, including sensitivity analyses and publication bias assessments. Results: The meta-analysis included 16 studies encompassing 1516 observations. Tourniquet use significantly increased cement penetration in average and cumulative analysis ( Conclusions: Tourniquet usage enhanced cement penetration but did not significantly affect surgical duration and pain; instead, it reduced blood transfusion rates. However, variability in surgical techniques and methodologies among included studies has contributed to the results. Future research must use standardized methodologies to resolve inconsistencies and confirm these results. Levels of Evidence: Level II.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.