Evidence map›Paper›PMID 41245686›Full record

ArticleClinical case reports2025

Biphasic Synovial Sarcoma of the Palatine Tonsil: A Case Report and Literature Review.

Ramiza Ramza Ramli, Shahzaib Maqbool, Abdur Rehman, Sadia Chaudhry, Imran Khan, Rahmat Gul Omarzai

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ramiza Ramza RamliDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Health Campus Universiti Sains Malaysia Kota Bharu Kelantan Malaysia.ORCID https://orcid.org/0000-0001-8196-321X
Shahzaib MaqboolInternal Medicine, HCA Healthcare Kansas City Missouri USA.
Abdur RehmanDepartment of Otorhinolaryngology Benazir Bhutto Hospital Rawalpindi Punjab Pakistan.ORCID https://orcid.org/0000-0001-6118-717X
Sadia ChaudhryDepartment of Otorhinolaryngology Benazir Bhutto Hospital Rawalpindi Punjab Pakistan.
Imran KhanNYC Health+Hospitals/Woodhull Brooklyn New York USA.
Rahmat Gul OmarzaiNangarhar Medical Faculty Jalalabad Afghanistan.ORCID https://orcid.org/0009-0009-9830-5649

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synovial sarcoma (SS) is a rare soft tissue tumor, accounting for 5%-10% of all soft tissue sarcomas, with an unusual occurrence in the head and neck region. This report presents a 29-year-old male with a biphasic SS of the left palatine tonsil, manifesting as progressive dysphagia, odynophagia, hoarseness, and left cervical lymphadenopathy. Clinical examination and imaging revealed a 4 × 4 mass arising from the left tonsil and obstructing the oropharyngeal inlet. Left tonsillectomy was done and the histopathological evaluation revealed a biphasic SS and negative margins. The diagnosis was further supported by a positive transducin-like enhancer of split-1 (TLE-1), SS translocation on chromosome 18 (SS18), and epithelial membrane antigen (EMA). The patient underwent chemotherapy and external beam radiotherapy (60 Gy in 30 fractions), with significant clinical improvement. This case highlighted the importance of a multidisciplinary approach in diagnosing and managing a rare head and neck SS. Furthermore, this is the first reported case from Pakistan, emphasizing the need for awareness in atypical locations.

Indexed as

fluorescencehead and neck neoplasmshumanin situ hybridizationpalatine tonsilsarcomaSS18 proteinsynovial

Identifiers

PMID41245686
PMCPMC12618274

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