Evidence map›Paper›PMID 41245662›Full record

ArticleJournal of pharmaceutical analysis2025

Label-free electrochemical aptasensing of cardiac cell secretomes in cell culture media for the evaluation of drug-induced myocardial injury.

Zelin Yang, Xilin Chen, Mingang Liao, Feng Liao, Wen Chen, Qian Shao, Bing Liu, Duanping Sun

Abstract read
In one paragraph

Article in Journal of pharmaceutical analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zelin YangGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Pharmaceutical Sciences, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Xilin ChenGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Pharmaceutical Sciences, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Mingang LiaoGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Pharmaceutical Sciences, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Feng LiaoGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Pharmaceutical Sciences, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Wen ChenGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Pharmaceutical Sciences, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Qian ShaoChongqing Engineering Research Center of Pharmaceutical Sciences, Chongqing Medical and Pharmaceutical College, Chongqing, 401331, China.
Bing LiuGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Pharmaceutical Sciences, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Duanping SunGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Pharmaceutical Sciences, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac troponin I (cTnI), a widely used biomarker for assessing cardiovascular risk, can provide a window for the evaluation of drug-induced myocardial injury. Label-free biosensors are promising candidates for detecting cell secretomes, since they do not require labor-intensive processes. In this work, a label-free electrochemical aptasensor is developed for

Indexed as

Antitumor drug evaluationCardiac troponin IElectrochemical aptasensorMetal-organic framework

Identifiers

PMID41245662
PMCPMC12613016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.