ArticleFrontiers in bioengineering and biotechnology2025
Design of a porous biodegradable internal fixation for the treatment of pauwels type III femoral neck fractures.
Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prolonged internal fixation in the femur can cause issues like osteosclerosis and stress masking, which hinder fracture recovery. AZ31b magnesium alloy has already been widely investigated and shown to be biocompatible and biodegradable. This study used finite element analysis to investigate stress changes during healing, aiming to find the best time for removing internal fixation and focuses on optimizing the structural design of internal fixation, using AZ31b magnesium alloy, to address issues like osteosclerosis and stress shielding in femoral neck fracture healing. This study focuses on optimizing structural design for the treatment of Pauwels III femoral neck fractures using cannulated screws. Pauwels III fractures are characterized by high shear stress and unstable fracture angles, making them prone to fixation failure. By optimizing the fixation method, the risk of complications such as osteosclerosis and stress shielding can be mitigated, ultimately improving clinical outcomes. The findings show that when cancellous bone heals but cortical bone does not, stress on the fracture surface decreases. Early removal of titanium internal fixation, followed by biodegradable porous internal fixation, allows for natural degradation during healing. We simulated stress evolution across healing stages via finite element modeling to determine optimal fixation replacement timing. Four AZ31b magnesium alloy porous structures (cubic, honeycomb, diagonally orientated, modified truncated pyramid) were designed; their equivalent elastic modulus and strength were evaluated through simulated compression tests, while permeability was analyzed using computational fluid dynamics (CFD). We found that the cubic and honeycomb structures were found to have higher permeability (6.23 × 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.