Evidence map›Paper›PMID 41245515›Full record

ArticleInternational journal of pharmaceutics: X2025

Regulation of hydrogen and oxidative stress in treating intestinal mucosa from ulcerative colitis.

Na Yu, Jingwen Xu, Jie Fan, Huimin Gao, Ting Wu, Yunfeng Zhu, Jing Xu, Xiaolin Li, Huae Xu, Xiaowei Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pharmaceutics: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Antioxidants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Na YuDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jingwen XuDepartment of Geriatrics, the Jurong People's Hospital of Jiangsu University, Zhenjiang, China.
Jie FanDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Huimin GaoDepartment of Pharmaceutics, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Ting WuDepartment of Pharmaceutics, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Yunfeng ZhuCollege of Materials Science and Engineering, Jiangsu Collaborative Innovation Centre for Advanced Inorganic Function Composites, Nanjing, China.
Jing XuThe Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, Yancheng, China.
Xiaolin LiDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Huae XuDepartment of Pharmaceutics, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Xiaowei LuDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a diffuse chronic inflammation in the superficial intestine. Excessive accumulation of reactive oxygen species (ROS) leads to the of the colorectal damage. As the anti-inflammation therapy needs to be last for at least 3-5 years, the drugs demand less toxicity. However, current treatments in the clinic are often accompanied by unavoidable adverse side effects. Hydrogen is a nontoxic antioxidant reagent with excellent permeability of biomembranes, which shows the potential in treating UC. A novel simply designed hydrogen storage particle, Magnesium Hydride (MgH

Indexed as

Controlled releaseHydrogenInflammationMagnesium hydrideOxidative stressUlcerative colitis

Identifiers

PMID41245515
PMCPMC12617788

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.