Evidence map›Paper›PMID 41245469›Full record

ArticleNew microbes and new infections2025

Epidemiological characteristics of pediatric respiratory pathogens and their association with climate in Wuxi, Chongqing, China.

Caili Luo, Xingyu Wang, Na Zhou

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Article in New microbes and new infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Caili LuoDepartment of Pediatrics, Wuxi People's Hospital, Wuxi County, Chongqing, China.
Xingyu WangLaboratory Department, Wuxi People's Hospital, Wuxi County, Chongqing, China.
Na ZhouDepartment of Pediatrics, Wuxi People's Hospital, Wuxi County, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute respiratory infections impose a disproportionate burden on pediatric populations, yet climate-pathogen interactions remain poorly characterized in rural China. Methods: We conducted a retrospective analysis of 7627 nasopharyngeal samples from children (<18 years) presenting with ARI symptoms at Wuxi People's Hospital (April 2023-March 2025). Six major pathogens--respiratory syncytial virus (RSV), influenza A/B (IAV/IBV), human rhinovirus (HRV), adenovirus (HAdV), and Mycoplasma pneumoniae (MP)--were detected by quantitative PCR. The association between meteorological factors and pathogen prevalence was examined. Results: HRV (22.18 %), IAV (18.54 %), and RSV (16.56 %) were the most prevalent pathogens, with RSV and HAdV showing higher hospitalization rates. Male children were more susceptible to all pathogens, particularly RSV (p = 0.024). Age-specific distributions revealed RSV dominance in infants (28 days-1 year) and toddlers (1-3 years), HRV and HAdV in preschoolers (3-6 years), and IAV and MP in school-aged children (6-18 years). Seasonal trends included year-round HRV and HAdV circulation, winter peaks for IAV and RSV, and an unexpected summer MP surge (26.88 % in June 2024). RSV exhibited an initial epidemic in 2023 (peak positivity: 52.27 % in April) with resurgence in October 2024. Climate analysis revealed temperature-dependent transmission: IAV/IBV correlated with colder temperatures. Notably, MP displayed atypical summer predominance in 2024, peaking at 26.88 % in June (25.2 °C, 77.3 % humidity). Conclusion: This study characterizes the epidemiological and climatic drivers of pediatric ARIs in Wuxi, China, underscoring pathogen-specific age distributions, seasonal anomalies, and climate interactions. The findings emphasize the need for sustained surveillance to monitor emerging respiratory threats and inform targeted interventions.

Indexed as

Climate-pathogen interactionsPediatric respiratory infectionsSeasonal epidemiology

Identifiers

PMID41245469
PMCPMC12617803

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.