ArticleFrontiers in physiology2025
Evaluating the physiological responses to treadmill exercise based on the 6-minute walk test in individuals with COPD across severity levels.
Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Integrating wearable technology with the 6 minute walk test to evaluate COPD patients.Frontiers in medicine · 2026Article
- Optimizing Interdisciplinary Referral Pathways for Chronic Obstructive Pulmonary Disease Management Across Cardiology and Pulmonology Specialties in the Kingdom of Saudi Arabia.Journal of clinical medicine · 2025Article
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Authors and funding
11 authors.
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Abstract
Background: Chronic obstructive pulmonary disease (COPD) limits exercise capacity and impacts lifestyle. While treadmill exercise aids rehabilitation, the 6-Minute Walk Test (6 MWT) serves as a vital assessment tool. The study examines whether physiological outcomes differ across COPD severities using the 6 MWT. Objectives: To compare physiological responses during treadmill exercise, based on 6 MWT results, across COPD severity levels per Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. Methods: A cross-sectional study involved COPD patients classified by 2023 GOLD standards from Jazan University Hospital Saudi Arabia. Of 40 initial participants, 35 were retained, excluding those with recent complications. Cardiopulmonary function was assessed by measuring heart rate and blood pressure with an automated monitor, while respiratory parameters were evaluated using a spirometer, all in accordance with the guidelines set by the American Thoracic Society. Results: 35 participants (87.5%), aged 40-75 years (mean 58.3 ± 9.8), completed the study, with 23:12 males to females. Participants averaged 382 ± 65 m in 6 MWT and 17 ± 5 min on treadmill. Forced expiratory volume (FEV1) showed strong correlation (r = 0.99) between exercises. ANOVA revealed significant heart rate differences across COPD severities (p = 0.0001). Paired t-tests showed differences in heart rate, oxygen saturation (SpO2), and respiratory rate between modalities (p < 0.05). Conclusion: The 6 MWT and treadmill exercise elicit distinct physiological responses in COPD patients, with disease severity affecting heart rate variations. These findings suggest 6 MWT may not directly predict treadmill exercise responses, emphasizing the need for tailored exercise prescriptions.
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