Evidence map›Paper›PMID 41245021›Full record

ArticleJPGN reports2025

Digestive autoimmune diseases mimicking gastrointestinal manifestations in children with sickle cell anemia: A report of three cases.

Saray Mesonero Cavia, Marta García Bernal, Maria Jose López Liñan, Roger García Puig

Abstract read
In one paragraph

Article in JPGN reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saray Mesonero CaviaDepartment of Pediatric Gastroenterology, Hepatology, and Nutrition Mutua Terrassa University Hospital Terrassa Barcelona Spain.ORCID https://orcid.org/0009-0000-9056-8297
Marta García BernalDepartment of Pediatric Hematology and Oncology Mutua Terrassa University Hospital Terrassa Barcelona Spain.
Maria Jose López LiñanDepartment of Pediatric Gastroenterology, Hepatology, and Nutrition Consorci Sanitari de Terrassa Hospital Terrassa Barcelona Spain.
Roger García PuigDepartment of Pediatric Gastroenterology, Hepatology, and Nutrition Mutua Terrassa University Hospital Terrassa Barcelona Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell anemia (SCA) is a genetic disorder that presents with a variety of systemic complications, including gastrointestinal (GI) manifestations. These GI symptoms can overlap with those of digestive autoimmune diseases (DAD) such as inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH), complicating the diagnosis and management. This study presents three cases of SCA patients diagnosed with DAD, highlighting the diagnostic challenges and therapeutic outcomes. Our goal is to stress how abdominal symptoms in SCA can mask the presence of DAD, leading to potential misdiagnoses. We review the implications of these findings in clinical practice and compare them to the literature to emphasize the importance of recognizing and differentiating these conditions to avoid delays in treatment.

Indexed as

autoimmune hepatitiscomorbidity in pediatricsdiagnostic challengeshemoglobin S diseaseinflammatory bowel disease

Identifiers

PMID41245021
PMCPMC12611588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.