Evidence map›Paper›PMID 41245018›Full record

ArticleJPGN reports2025

Rates of parent-reported allergic conditions in children at-risk of celiac disease.

Timothy Sun, Victoria Kenyon, Francesco Valitutti, Alessio Fasano, Victoria Martin, Maureen M Leonard

Abstract read
In one paragraph

Article in JPGN reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Timothy SunPediatric Allergy Immunology, Mass General Hospital for Children Harvard Medical School Boston Massachusetts USA.
Victoria KenyonCenter for Celiac Research and Treatment, Mass General Hospital for Children Harvard Medical School Boston Massachusetts USA.
Francesco ValituttiDepartment of Medicine and Surgery, Pediatric Unit University of Perugia Perugia Italy.
Alessio FasanoCenter for Celiac Research and Treatment, Mass General Hospital for Children Harvard Medical School Boston Massachusetts USA.
Victoria MartinPediatric Gastroenterology, Mass General Hospital for Children Harvard Medical School Boston Massachusetts USA.
Maureen M LeonardCenter for Celiac Research and Treatment, Mass General Hospital for Children Harvard Medical School Boston Massachusetts USA.ORCID https://orcid.org/0000-0002-5955-5102

Funding

Prospective Multi-Omic Analysis of At-Risk infants to Model Celiac Disease PathogenesisK23DK122127 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI LEONARD, MAUREEN MICHELLE · 2019 to 2023
$1.2M
Systems approach to elucidate the microbiome's influence on the development of food allergies early in lifeK23AI151556 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARTIN, VICTORIA MACKENZIE · 2021 to 2025
$998k
The Celiac Disease Genomic, Environmental, Microbiome, and Metabolomic (CD-GEMM) Prospective Cohort StudyR56AI169645 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI FASANO, ALESSIO · 2023 to 2023
$823k
The Celiac Disease Genome, Environment, Microbiome, and Metabolome (CD-GEMM) prospective cohort studyR56AI156711 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI FASANO, ALESSIO · 2021 to 2021
$410k
NIAID NIH HHS K23 AI151556NIAID NIH HHS R56 AI156711NIAID NIH HHS R56 AI169645NIDDK NIH HHS K23 DK122127
6 · The paper itself

Abstract

Allergies and other chronic immune mediated conditions are becoming increasingly common. Here we utilized a prospective birth cohort called the Celiac Disease Genomic Environmental Microbiome and Metabolomic (CDGEMM) study to examine the frequency of parent reported allergic conditions and their association with celiac disease (CeD). We examined 271 children at-risk of CeD from the United States and found a high frequency of allergic conditions. In our overall cohort, 19.8% reported food protein-induced allergic proctocolitis (FPIAP), 12.5% reported IgE-mediated food allergy, and 14.7% reported atopic dermatitis. Among the 23 children with CeD, 21.74% had FPIAP, 8.7% had an IgE-mediated food allergy, and 21.74% had atopic dermatitis. No significant association between allergic conditions and CeD was found (

Indexed as

allergyautoimmunecow's milk protein allergyfood allergyimmune

Identifiers

PMID41245018
PMCPMC12611602

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.