ArticleOphthalmology science2026
Anterior Chamber Inflammation and Descemet Membrane Endothelial Keratoplasty: An Anterior Segment-OCT-Based Analysis.
Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Comparative efficacy of Nd:YAG laser peripheral iridotomy and surgical iridectomy in modulating perioperative subclinical inflammation after DMEK.Acta ophthalmologica · 2026Article
- Dome-Shaped Protrusions on Descemet's Membrane in Bullous Keratopathy: Identification and Histopathological Examination.Translational vision science & technology · 2026Observational
- Bullous keratopathy associated with a shallow anterior chamber: An anatomical risk phenotype for corneal endothelial decompensation.PloS one · 2026Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To assess anterior chamber (AC) subclinical inflammation using a noninvasive method in patients undergoing Descemet membrane endothelial keratoplasty (DMEK). Design: Retrospective interventional case series. Participants: This study included 83 eyes from 73 patients who underwent DMEK surgery and 15 control eyes from 15 healthy individuals. Methods: The number of hyperreflective dots representing AC cells and optical density ratio (aqueous-to-air relative intensity [ARI] index) for flare quantification were calculated from anterior segment-OCT images. Aqueous-to-air relative intensity index and AC cells were calculated preoperatively and postoperatively at 1 week (T1), 1 month (T2), and 3 months (T3) after DMEK surgery. Baseline values were compared with a healthy control group. Main Outcome Measures: Anterior chamber cell count and ARI index over time; association with postoperative posterior stromal ripples (PSRs) and rebubbling. Results: Baseline ARI index was significantly higher in the DMEK group compared with controls, whereas no significant difference in AC cell count was observed. Anterior chamber cell count increased postoperatively from a median of 1.1 cells (0.6-2.1) at baseline to 3.5 (1.7-5.3) at T1 ( Conclusions: Anterior segment-OCT enables noninvasive detection of subclinical inflammation after DMEK surgery. The presence of markers of inflammation can increase the risk of early postoperative complications. Financial Disclosures: The authors have no proprietary or commercial interest in any materials discussed in this article.
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