Evidence map›Paper›PMID 41244966›Full record

ArticleASM case reports2025

Resolution of acute rejection in a bilateral double-lung transplanted cystic fibrosis patient following phage intervention.

Marco Pardo-Freire, Mireia Bernabéu-Gimeno, Benjamin K Chan, Paul E Turner, Isabel Sánchez-Romero, Myriam Aguilar-Pérez, Marta Erro-Iribarren, Pilar Domingo-Calap

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ASM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco Pardo-Freire *Institute for Integrative Systems Biology, University of Valencia-CSIC, Paterna, Spain.
Mireia Bernabéu-Gimeno *Institute for Integrative Systems Biology, University of Valencia-CSIC, Paterna, Spain.
Benjamin K ChanDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA.
Paul E TurnerDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA.
Isabel Sánchez-RomeroDepartment of Microbiology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Myriam Aguilar-PérezDepartment of Pneumonology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Marta Erro-IribarrenDepartment of Pneumonology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Pilar Domingo-CalapInstitute for Integrative Systems Biology, University of Valencia-CSIC, Paterna, Spain.ORCID https://orcid.org/0000-0003-2829-8809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial resistance is a major threat to human health worldwide, requiring investigation into alternative therapeutics such as phage therapy. Phages have been used to treat numerous multidrug-resistant infections recently, particularly in people with cystic fibrosis (CF) who are predisposed to infection from Case Summary: Here, we report the use of phage therapy to treat a chronic Conclusion: This case underscores the potential of phage therapy to complement traditional treatments in managing chronic bacterial infections in CF patients, though further studies are needed to optimize treatment protocols and understand the role of phages in modulating the bacterial population.

Indexed as

antimicrobial resistancecystic fibrosislung transplantationphage therapy

Identifiers

PMID41244966
PMCPMC12530250

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.