ArticleFrontiers in oncology2025
Intraductal papilloma of breast with carcinoma
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The simultaneous occurrence of intraductal papilloma and malignant breast lesions is rare, as is the presence of ductal carcinoma Case presentation: A 49-year-old female with a decade-long history of pulmonary tuberculosis presented with a right breast mass, first noticed 10 days prior. Color Doppler ultrasound identified a hypoechoic nodule in the right breast, and breast MRI, both with and without contrast, revealed multiple regions of abnormal enhancement in the right breast, along with enlarged axillary lymph nodes. Tissue biopsy confirmed intraductal papilloma with malignant transformation in some areas (low-grade DCIS). Axillary lymph node biopsy was positive for tuberculosis. The patient underwent right mastectomy, and follow-up after one month showed no recurrence. Conclusion: Tuberculosis remains prevalent in developing countries, and this patient's history of pulmonary tuberculosis spans over 10 years. The co-occurrence of breast cancer and axillary tuberculous lymphadenitis is unusual. A prompt and accurate diagnosis of breast cancer is vital, involving preoperative imaging, biopsy, and pathological assessment during and after surgery. Once diagnosed, a treatment plan tailored to the characteristics of carcinoma
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