Evidence map›Paper›PMID 41244875›Full record

ArticleFrontiers in psychiatry2025

Beyond diagnosis: symptom patterns across complex PTSD and borderline personality disorder.

Joe J Simon, Kristin Spiegler, Kadiatou Coulibaly, Marion A Stopyra, Hans-Christoph Friederich, Oliver Gruber, Christoph Nikendei

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joe J SimonDepartment of General Internal Medicine and Psychosomatics, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Kristin SpieglerDepartment of Clinical Psychology and Psychotherapy, Institute of Psychology, Heidelberg University, Heidelberg, Germany.
Kadiatou CoulibalyDepartment of General Internal Medicine and Psychosomatics, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Marion A StopyraDepartment of General Internal Medicine and Psychosomatics, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Hans-Christoph FriederichDepartment of General Internal Medicine and Psychosomatics, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Oliver GruberDepartment of General Psychiatry, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Christoph NikendeiDepartment of General Internal Medicine and Psychosomatics, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Complex post-traumatic stress disorder (cPTSD) and borderline personality disorder (BPD) share overlapping clinical features, complicating accurate diagnosis and treatment. This overlap has fueled ongoing discussions regarding whether cPTSD and BPD should be considered as distinct diagnostic categories. To contribute to this debate, the current study aimed to clarify symptomatic similarities and differences between cPTSD and BPD using psychometric assessments. Methods: 97 female participants were recruited, including 34 patients with cPTSD, 25 with BPD and 38 healthy controls. All participants completed a battery of validated psychometric instruments assessing depression, anxiety, difficulties in emotion regulation, psychodynamic dysfunction, guilt-related distress, health-related functioning, as well as trauma-related symptoms and borderline personality traits. Differences between groups were analyzed using one-way ANOVAs, followed by Results: Patients with cPTSD reported significantly higher levels of trauma exposure, posttraumatic symptom severity, dissociative symptoms, affective symptoms and functional impairment compared to both BPD patients and healthy controls. In contrast, no significant differences were found between cPTSD and BPD in borderline symptom severity, anxiety, difficulties in emotion regulation, guilt-related distress and psychodynamic dysfunction. Conclusions: The results highlight trauma-related symptoms as key differentiators between cPTSD and BPD, supporting the conceptualization of cPTSD as a distinct disorder. However, as ICD-11 specific diagnostic instruments were not applied, the findings should be interpreted with appropriate caution.

Indexed as

affective symptomsborderline personality disordercomplex post-traumatic stress disorderdissociationfunctional impairmenttrauma

Identifiers

PMID41244875
PMCPMC12612632

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.