ArticleOpen forum infectious diseases2025
Long-Term Outcomes of Young Adults With Perinatal Human Immunodeficiency Virus (HIV) Infection in the United States and Puerto Rico.
Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Data on mortality, clinical events, viral load (VL), and immunosuppression among young adults aging with perinatally acquired human immunodeficiency virus (YAPHIV) are limited. Methods: Among YAPHIV ≥ 18 years in the Pediatric HIV/AIDS Cohort Study, we calculated incident mortality, CDC-C/WHO-4 rates, and proportion of person-years (PY) with elevated VL (≥200 copies/mL) and immunosuppression (CD4 < 200 cells/mm Results: Six hundred seventeen participants had median follow-up of 6.5 years; at baseline, 63% were 18-21 years, 61% were female, 63% self-reported as Black, median CD4 count was 561 cells/mm Conclusions: There is excess mortality with age for YAPHIV, particularly for Black YAPHIV. Interdisciplinary interventions are needed to improve treatment outcomes for YAPHIV at highest identified risk.
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