ArticleiScience2025
Microbial communities experienced during early development shape the host immune system and epigenome.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Environmental microbial communities and host selection shape larval microbiomes.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shaping of the epigenomic landscape by local environments during early life stages could initiate adaptive developmental plasticity, allowing organisms to optimize their phenotypes for local conditions. Elevated seawater temperature can increase bacterial loads and pathogen spread, making it imperative to understand how physiological and molecular traits of marine organisms are impacted, especially the immune system. Experimentally manipulated temperatures and microbial environments during embryogenesis resulted in changes in larval morphology, immune cell development, and the epigenome of the purple sea urchin (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.