ArticlePakistan journal of medical sciences2025
MELD 3.0 score in prediction of varices and comparison with its previous versions in patients undergoing esophago-gastro-duodenoscopy for variceal screening or band ligation.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Comparative Accuracy of Clinical and Inflammatory Scores for Predicting Mortality and Rebleeding After Acute Gastroesophageal Variceal Bleeding.Journal of clinical medicine · 2026Article
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5 authors.
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Abstract
Objective: To compare MELD, MELDNa & MELD 3.0 score values with presence of varices in patients undergoing esophago-gastro-duodenoscopy for variceal screening or band ligation. The other objective was to estimate cut-off values of various MELD variants in prediction of varices using Area Under Receiver Operator Curve (AUROC). Methodology: This cross-sectional study was conducted in Department of Medicine/Gastroenterology at Dow Medical College, Karachi during the period 20th November 2022 to 19th September 2024. All patients of either gender of age between 18 to 65 years undergoing screening endoscopy were included in the study after informed consent. MELD, MELDNa & MELD 3.0 scores were calculated, grades of oesophageal varices were recorded. Results: Total of 321 patients were included. Highest scores for presence of varices were reported by MELD 3.0 (19.21). No difference was found for variceal presence on gender in MELD 3.0 scores but MELD & MELDNa scores were significantly lower in females. All MELD variants showed significant area under curve on ROC with highest AUC in MELDNa. Regression analysis for MELD variants showed that 88.8% of MELD 3.0 score was influenced by age, gender, bilirubin, sodium, INR, creatinine & albumin. Age, sodium & albumin affected negatively on the score. In both MELD and MELDNa scores albumin levels did not have any significant effect on score. Conclusions: All MELD variants have good predictability for varices at their different scores with MELDNa showing highest AUC. MELD 3.0 gives more weightage to female gender by allocating them score that are not different from males, while the other two allocate lower scores to females.
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