ArticlePakistan journal of medical sciences2025
The efficacy and clinical significance of microsurgery on cognitive function, activities of daily living, and serum biomarkers in patients with glioma.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Current Pharmacotherapeutic Strategies in Diffuse Gliomas: Focus on Glioblastoma, IDH-Wildtype, and Emerging Targeted Therapies for IDH-Mutant Tumors.Pharmaceuticals (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the efficacy of microsurgery on cognitive function, activities of daily living (ADL), and serum biomarkers in patients with glioma. Methodology: This was a retrospective study. A total of 120 eligible patients with glioma were enrolled from Baoding No.1 Hospital from May 2023 to December 2024 and randomly divided into two groups. The control group underwent conventional craniotomy for tumor resection, while the study group opted for microsurgery. The surgical outcomes were compared between the two groups. Additionally, levels of inflammatory markers (interleukin-6 [IL-6], serum amyloid A [SAA], C-reactive protein [CRP], and tumor necrosis factor-alpha [TNF-α]) and cytokines (arginine vasopressin [AVP], oxytocin [OT], and β-endorphin [β-EP]), cognitive function, and ADL were assessed before and after surgery. Results: The surgical outcomes of study group were significantly superior to control group. After treatment, levels of IL-6, CRP, SAA, and TNF-α were significantly lower in the study group than in the control group, while the levels of AVP, OT, and β-EP were significantly higher in the study group ( Conclusion: Microsurgery is an effective, efficient treatment modality for the treatment of glioma, which is worthy of clinical promotion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.