Evidence map›Paper›PMID 41244511›Full record

ArticleSchizophrenia research. Cognition2026

Theory of mind difficulties in people with social anhedonia: Evidence from behavioural and task-based functional magnetic resonance imaging findings.

Yuan Cao, Ding-Ding Hu, Winnie W Y So, Yi Wang, Xiao-Dong Guo, Raymond C K Chan, David H K Shum

Abstract read
In one paragraph

Article in Schizophrenia research. Cognition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuan CaoDepartment of Social Work and Social Administration, The University of Hong Kong, Hong Kong, China.
Ding-Ding HuNeuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, China.
Winnie W Y SoDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China.
Yi WangNeuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, China.
Xiao-Dong GuoNeuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, China.
Raymond C K ChanNeuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, China.
David H K ShumMental Health Research Center, The Hong Kong Polytechnic University, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Social Anhedonia (SA) is recognised as a negative symptom of the schizophrenia spectrum. Despite the emerging evidence of general impairment in Theory of Mind (ToM), the behavioural manifestation and underlying neural mechanisms of ToM deficits in SA remain unclear. The current study therefore adopted a multidimensional assessment approach to examine the effect of SA on ToM ability behaviourally and using fMRI. Methods: A total of 47 participants with high SA ( Results: The participants with low SA showed better performance for first-order ToM than for second-order ToM. However, those with high SA did not show such a differential effect. Based on the fMRI results, the low SA group showed more activation than the high SA group in the medial frontal cortex and posterior cingulate cortex in second-order ToM than in first-order ToM. Conclusion: The results demonstrate the impairment of ToM performance among those with high SA and highlight that it is crucial to examine the pattern of results rather than solely focusing on general ToM.

Indexed as

fMRINeuroimagingSocial anhedoniaSocial cognitionTheory of mind

Identifiers

PMID41244511
PMCPMC12617822

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.