Evidence map›Paper›PMID 41244375›Full record

ArticleACS omega2025

Biomineralization Enhanced Antibacterial Effect of Lysozyme and Promotes Wound Healing.

Lili Chen, Hao Wang, Wei Li, Jilu Zheng, Chunzhao Liu, Xiang Ji, Chunlei Liu, Xiaopeng Lan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lili ChenQingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, PR China.
Hao WangQingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, PR China.
Wei LiQingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, PR China.
Jilu ZhengQingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, PR China.
Chunzhao LiuInstitute of Biochemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, PR China.
Xiang JiQingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, PR China.
Chunlei LiuQingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, PR China.
Xiaopeng LanQingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, PR China.ORCID https://orcid.org/0000-0003-1482-8952

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysozyme (Lys) is a natural protein known for its bacteriostatic properties. However, its effectiveness against Gram-negative bacteria is limited, which poses challenges for its application in clinical settings. In this study, we developed a flower-like nanostructure composed of cobalt phosphate and Lys. This novel formulation significantly improved the inhibition of Gram-negative bacteria. The cobalt phosphate nanoflowers demonstrated the ability to effectively eliminate resistant bacterial strains under physiological conditions while exhibiting extremely low long-term systemic toxicity. These promising results indicate the potential of this approach for further biomedical applications and clinical translation.

Identifiers

PMID41244375
PMCPMC12612895

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.