Evidence map›Paper›PMID 41244349›Full record

ArticleBioengineering & translational medicine2025

Engineered endothelial cells targeting and dihydrotanshinone I loaded bacterial extracellular vesicles for atherosclerosis therapy.

Rong-Rong Zhu, Xue-Liang Zhou, Yan-Wei Liu, Ri Xu, Peng Deng, Zhong-Yong Liu

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rong-Rong ZhuDepartment of Cardiology The Affiliated Hospital of Jiangxi University of Chinese Medicine Nanchang China.
Xue-Liang ZhouDepartment of Cardiovascular Surgery, the First Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang China.
Yan-Wei LiuDepartment of Cardiology The Affiliated Hospital of Jiangxi University of Chinese Medicine Nanchang China.
Ri XuDepartment of Cardiology The Affiliated Hospital of Jiangxi University of Chinese Medicine Nanchang China.
Peng DengDepartment of Cardiology The Affiliated Hospital of Jiangxi University of Chinese Medicine Nanchang China.
Zhong-Yong LiuDepartment of Cardiology The Affiliated Hospital of Jiangxi University of Chinese Medicine Nanchang China.ORCID https://orcid.org/0000-0001-8300-4709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is a complex cardiovascular disease characterized by endothelial dysfunction, dyslipidemia, and immune-inflammatory responses, leading to arterial plaque formation and potentially fatal complications such as myocardial infarction and stroke. Traditional treatments, such as statins, often pose challenges due to their side effects and limited efficacy. In this study, we explore a novel therapeutic approach utilizing engineered endothelial cells (ECs) targeting probiotic extracellular vesicles loaded with dihydrotanshinone I (DHT) (EC-BEVs

Indexed as

atherosclerosisbacterial extracellular vesiclesdihydrotanshinone Iendothelial cells

Identifiers

PMID41244349
PMCPMC12617545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.