Evidence map›Paper›PMID 41244293›Full record

ArticleASM case reports2025

A case of enterovirus D68-associated acute flaccid myelitis in an immunocompromised adult, Australia.

Nathaniel Lizak, Grace Butel-Simoes, Eike Steinig, Belinda Cruse, Edrich Rodrigues, Kirsty Buising, Joe Sasadeusz, Marcelina Krysiak, Bruce Thorley, Matthew Kaye and 8 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ASM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Nathaniel Lizak *Department of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Grace Butel-Simoes *Victorian Infectious Diseases Reference Laboratory, The Royal Melbourne Hospital at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Eike SteinigDepartment of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Belinda CruseDepartment of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Edrich RodriguesDepartment of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Kirsty BuisingDepartment of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Joe SasadeuszDepartment of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Marcelina KrysiakDepartment of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Bruce ThorleyNational Enterovirus Reference Laboratory, Victoria Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia.
Matthew KayeNational Enterovirus Reference Laboratory, Victoria Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia.
Leon CalyVictorian Infectious Diseases Reference Laboratory, The Royal Melbourne Hospital at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Jean MoselenVictorian Infectious Diseases Reference Laboratory, The Royal Melbourne Hospital at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Ivana SavicVictorian Infectious Diseases Reference Laboratory, The Royal Melbourne Hospital at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Andrew W RobertsClinical Haematology, Royal Melbourne Hospital and Peter MaCallum Cancer Centre, Melbourne, Australia.
Katherine BondDepartment of Microbiology, Royal Melbourne Hospital, Melbourne, Australia.
Chuan Kok LimVictorian Infectious Diseases Reference Laboratory, The Royal Melbourne Hospital at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Deborah A WilliamsonDepartment of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0001-7363-6665
Prashanth RamachandranDepartment of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0001-8464-1355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute flaccid myelitis (AFM) is a predominantly pediatric, polio-like syndrome associated with enterovirus D68. AFM in adults is rare, reported predominantly in immunocompromised hosts. Case Summary: Here, we report detection of enterovirus D68 in an immunocompromised Australian adult, specifically the B3 subgroup. Conclusion: This strain is phylogenetically linked to the 2018 AFM outbreaks in the USA and to documented cases in 2022 in France.

Indexed as

acute flaccid myelitisEV-D68

Identifiers

PMID41244293
PMCPMC12584186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.