Evidence map›Paper›PMID 41244278›Full record

ArticleASM case reports2025

Sudden deaths of two dogs in a breeding colony associated with enteropathogenic

Maho Okumura, Nathan Helgert, Katharine Tuohy, Donna J Kelly, Stephen D Cole

Abstract readCase Reports
In one paragraph

Article in ASM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maho OkumuraUniversity of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.
Nathan HelgertUniversity of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania, USA.
Katharine TuohyUniversity of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.
Donna J KellyUniversity of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania, USA.
Stephen D ColeUniversity of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-2681-0082

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This case report describes the peracute deaths of two healthy pups in a breeding facility associated with enteropathogenic Case Summary: A 7-week-old male and an 8-week-old female intact mixed-breed dogs were found deceased, shortly after routine examination with no preceding clinical signs. Post-mortem examination revealed multiple organ abnormalities, including bronchopneumonia with alveolar collapse, hepatic lipidosis, gastrointestinal inflammation, and bacterial colonization in the lungs and intestines. Bacterial cultures from the lungs and intestines of both pups yielded multiple bacterial species. WGS of six Conclusion: The findings suggest a role of EPEC and ExP-NTEC in the sudden deaths of neonatal dogs, possibly exacerbated by a naïve immune system. It is challenging to fully characterize the pathogenesis and potential risk factors as

Indexed as

canine sudden deathEPEC infection in caninesEscherichia coliExP-NTEC in canines

Identifiers

PMID41244278
PMCPMC12584188

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.