Evidence map›Paper›PMID 41244196›Full record

ArticleAsian journal of transfusion science

Time-deferred consequences: A deep dive into delayed adverse reactions among whole blood donors.

Romesh Jain, Anubhav Gupta, Davood Bava, Vilasini Patil, Pratul Sinha, Sachin Garg, Snehashish Mishra, Shubhangi Jain

Abstract read
In one paragraph

Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Romesh JainDepartment of Transfusion Medicine and Blood Bank, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Anubhav GuptaDepartment of Transfusion Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Davood BavaDepartment of IHBT, NIMS, Jaipur, Rajasthan, India.
Vilasini PatilDepartment of Transfusion Medicine and Blood Bank, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Pratul SinhaDepartment of Transfusion Medicine and Blood Bank, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Sachin GargDepartment of Blood Centre, KCGMC, Karnal, Haryana, India.
Snehashish MishraDepartment of Transfusion Medicine and Blood Bank, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Shubhangi JainDepartment of Obstetrics and Gynecology, Ex SRF All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Blood Donor Health is an important component in blood transfusion services. The retention of blood donors is important, if not less than the recruitment of new blood donors. Despite the recognized importance of donor health, several challenges impede the retention of donors. These include the donor experience in the form of adverse reactions ranging from mild to severe which can be immediate or delayed. Such experiences can deter blood donors from returning to donor pool. Our study focuses on the incidence, types, and impacts of delayed adverse reactions (DARs) among whole blood donors in an Indian context, aiming to enhance donor retention through improved safety and experience. MATERIALS AND

methodsA prospective observational study was conducted at a premier tertiary care and research institute in Central India. The study included 1615 whole blood donors over 6-month period and used telephonic interviews on day 7 for postdonation follow-up. Statistical analysis was performed using Epi Info software, focusing on donor demographics, incidence, and types of DARs, and their association with various factors.

resultsThe study found a 6.31% incidence of DARs, the most common being generalized weakness, followed by bruising and painful arms. A higher body mass index (BMI) significantly associated with an increased incidence of DARs. Notably, 75.5% of donors who experienced DARs expressed reluctance toward future blood donations, compared to 2.8% of those without DARs, highlighting the impact of DARs on donor retention.

conclusionThis study underscores the importance of monitoring and managing DARs to enhance donor safety and experience, thereby improving retention rates. It suggests the need for systematic follow-up protocols, focused strategies for high-risk groups, enhanced support for female donors, standardization in definitions, and robust donor education programs. The findings contribute to the knowledge base on DARs in blood donation, ensuring a reliable blood supply crucial for healthcare.

Indexed as

Adverse donor reactionsblood supply managementdonor retentionhemovigilancevasovagal reactions

Identifiers

PMID41244196
PMCPMC12614717

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.