ArticleAsian journal of transfusion science
A study to identify severe acute respiratory syndrome coronavirus 2 in erythrocytes of patients suffering from coronavirus disease-19 at an Apex tertiary care institute in Andhra Pradesh, South India.
Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextCoronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) in the latest coronavirus disease (COVID-19) pandemic has been shown to cause a rise of ferritin levels through a possible viremia. Hemoglobin in the erythrocyte (red blood cell [RBC]) is a potential source of ferritin and we hypothesized that erythrocyte might be infected by this virus. Any infected RBC in asymptomatic blood donors might become a huge threat to the blood.
aimThe aim of the study is to identify the presence of SARS-CoV-2 ribonucleic Acid (RNA) in RBC of patients suffering from COVID-19 disease. SETTING AND
designA prospective study was performed to identify the presence of SARS-CoV-2 RNA in erythrocytes of patients with COVID-19. SUBJECTS AND
methodsTen samples were collected from patients with COVID-19 at different times during their admission. After sampling, these were processed and stored like Packed red blood cells (PRBCs). These units were further processed by washing or leukoreduction with further sampling. All these samples were tested for the detection of SARS-CoV-2 RNA by real-time-polymerase chain reaction. STATISTICAL ANALYSIS: Descriptive statistics with Microsoft Excel were performed.
resultsThe study could not identify the SARS-CoV-2 virus in the erythrocytes or plasma of infected patients.
conclusionSARS-CoV-2 virus may not be a transfusion transmissible infection, however, this needs to be confirmed with a larger study. It is recommended to have a lookout hemovigilance policy given newer variants of SARS-CoV-2 and for possible new viruses that may emerge in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.