ArticleAsian journal of transfusion science
Therapeutic red blood cell exchange in a sickle cell disease patient with acute bone pain crisis: Our experience in a tertiary care center.
Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
Transfusion therapy remains the main stay of treatment for patients with sickle cell anemia for several years. However, repeated transfusions might result in iron overload and alloimmunization in sickle cell disease (SCD) patients. Automated red cell exchange (RCE) is a therapeutic procedure, in which deformed red blood cells of the patient were separated, removed, and exchanged with normal red blood cells of blood donor through a dedicated apheresis machine. It is an evolving and effective procedure in reducing the sickle cell load and its associated complications. Sickle cell crisis is a life-threatening and an emergency condition encountered in SCD patients, which requires prompt intervention and management. We would like to report our experience with one such case of SCD with acute bone pain crisis, in whom therapeutic automated RCE was initiated. This successful intervention promptly reduced the patient symptoms and also effectively decreased the Hemoglobin S concentration from 74% to 18%, which highlights the importance of RCE procedure.
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