Evidence map›Paper›PMID 41244134›Full record

ReviewAmerican journal of cancer research2025

The dual role of SLC7A11 in tumor drug resistance: mechanisms, challenges, and therapeutic potential.

Yulin Guo, Xiaoying Chen, Jingwen Hu, Yuting Su, Fuqiang Yin, Xia Liu

Abstract readReview
In one paragraph

Review in American journal of cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yulin GuoKey Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education, Institute of Neuroscience and Guangxi Key Laboratory of Brain Science, School of Basic Medical Sciences, Guangxi Medical University 22 Shuangyong Rd., Nanning 530021, Guangxi, P. R. China.
Xiaoying ChenKey Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education, Institute of Neuroscience and Guangxi Key Laboratory of Brain Science, School of Basic Medical Sciences, Guangxi Medical University 22 Shuangyong Rd., Nanning 530021, Guangxi, P. R. China.
Jingwen HuKey Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education, Institute of Neuroscience and Guangxi Key Laboratory of Brain Science, School of Basic Medical Sciences, Guangxi Medical University 22 Shuangyong Rd., Nanning 530021, Guangxi, P. R. China.
Yuting SuCollaborative Innovation Center of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by The Province and Ministry, Guangxi Medical University 22 Shuangyong Rd., Nanning 530021, Guangxi, P. R. China.
Fuqiang YinSchool of Life Sciences and Medical Engineering, Guangxi Medical University 22 Shuangyong Rd., Nanning 530021, Guangxi, P. R. China.
Xia LiuKey Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education, Institute of Neuroscience and Guangxi Key Laboratory of Brain Science, School of Basic Medical Sciences, Guangxi Medical University 22 Shuangyong Rd., Nanning 530021, Guangxi, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor drug resistance is a major factor in cancer treatment failure. SLC7A11 is characterized as a light-chain subunit antiporter of the Xc

Indexed as

autophagydisulfidptosisdrug resistanceferroptosisSLC7A11

Identifiers

PMID41244134
PMCPMC12616170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.