Evidence map›Paper›PMID 41244086›Full record

ArticleTropical parasitology

Sumeeta Khurana, Rimjhim Kanaujia, Megha Sharma, Chayan Sharma, Amit Gupta

Abstract read
In one paragraph

Article in Tropical parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sumeeta KhuranaDepartment of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rimjhim KanaujiaDepartment of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Megha SharmaDepartment of Microbiology, All India Institute of Medical Sciences, Bilaspur, Himachal Pradesh, India.
Chayan SharmaDepartment of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Amit GuptaDepartment of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Materials and Methods: In a prospective analysis, corneal scrapings, CL, and lens solution specimens processed in the department of parasitology between January 2019 and December 2021 were subjected to microscopy, axenic culture on nonnutrient agar, and 18SrRNA PCR. The amplified products were subjected to gene sequencing, and a phylogenetic tree was constructed using available sequences in the database. Results: Ten cases of AK were identified by culture and PCR during the study period. Sequence analysis and phylogenetic tree revealed that nine were genotype T4 and one was T5. The mean age of the patients was 29.5 years (range: 16-39 years), and male: female was 9:1. History of CL wearing was present only in four patients and extended wear in only one. Another patient had a history of ocular trauma, while five others had no risk factor. All were treated with polymyxin, polyhexamethylene biguanide, and voriconazole, and two underwent therapeutic keratoplasty. Conclusion: A high index of suspicion should be kept in patients even without classical AK risk factors. Microbiological diagnosis along with genotyping would add to the increasing database of global AK cases.

Indexed as

Acanthamoebafree-living amebagenotypekeratitis

Identifiers

PMID41244086
PMCPMC12617585

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.