Evidence map›Paper›PMID 41244049›Full record

ArticleFrontiers in endocrinology2025

Hengpan Yao, Zhiyi Xia, Yijing Liu, MengJun Dong, Kairui Yang, Fang Zhou

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hengpan YaoDepartment of Digestion, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, Henan, China.
Zhiyi XiaDepartment of Digestion, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, Henan, China.
Yijing LiuDepartment of Digestion, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, Henan, China.
MengJun DongDepartment of Digestion, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, Henan, China.
Kairui YangDepartment of Digestion, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, Henan, China.
Fang ZhouDepartment of Digestion, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With the rising global prevalence of childhood obesity, the incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) in pediatric and adolescent populations is also increasing. The genetic mechanisms underlying MASLD remain incompletely elucidated. This study aimed to investigate the roles of eight genetic loci- Methods: A total of 350 children and adolescents aged 7-17 years were enrolled, including 196 with MASLD (case group) and 154 healthy controls. Demographics, medical history, anthropometric measurements, and hepatic B-ultrasound data were collected. Fasting morning blood samples were obtained for biochemical analysis and genotyping. Statistical analyses included chi-square tests, Fisher's exact tests, and multivariate logistic regression to identify predictive factors for pediatric MASLD. Results: The allele frequencies of Conclusion: The

Indexed as

Fatty LiverGenetic Predisposition to DiseaseLipaseMembrane ProteinsMetabolic DiseasesPolymorphism, Single NucleotideAcyltransferasesAdolescentCase-Control StudiesChildChinaFemaleGenotypeHumansMalePhospholipases A2, Calcium-IndependentAcyltransferasesLipaseMembrane ProteinsPhospholipases A2, Calcium-IndependentPNPLA3 protein, humanTM6SF2 protein, humangeneticsgenetic susceptibilityMASLDpediatric hepatologyPNPLA3polymorphismTM6SF2

Identifiers

PMID41244049
PMCPMC12615210

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.