Evidence map›Paper›PMID 41244018›Full record

ArticlePlastic and reconstructive surgery. Global open2025

Does Size Matter? Exploring the Impact of Acellular Dermal Matrix Dimensions on Complications in Immediate Breast Reconstruction.

Aviella Goodman Gabay, Eva Nassar, Ronen Toledano, Yotam Teldan, Ron Skorochod, Tali Bdolah-Abram, Adi Maisel Lotan, Rami Binenboym, Yoav Gronovich

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Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aviella Goodman GabayFrom the Plastic and Reconstructive Surgery Department, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
Eva NassarFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Ronen ToledanoFrom the Plastic and Reconstructive Surgery Department, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
Yotam TeldanFrom the Plastic and Reconstructive Surgery Department, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
Ron SkorochodFrom the Plastic and Reconstructive Surgery Department, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
Tali Bdolah-AbramFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Adi Maisel LotanFrom the Plastic and Reconstructive Surgery Department, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
Rami BinenboymFrom the Plastic and Reconstructive Surgery Department, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
Yoav GronovichFrom the Plastic and Reconstructive Surgery Department, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent years have seen an increase in prepectoral immediate implant-based reconstructions, requiring larger acellular dermal matrices (ADMs) for implant coverage. Previous studies have suggested a potential rise in infection, flap necrosis, and seroma rates with ADM use in breast reconstructions. However, to our knowledge, no data exist to determine whether these complications are due to the presence of ADM itself or its size. This study aimed to investigate the correlation between ADM size and the incidence of postoperative complications. Methods: A retrospective, single-center analysis was conducted on 229 women (297 breasts) undergoing immediate breast reconstruction with ADM. Reconstructions were stratified into 2 cohorts: small ADM (≤128 cm², n = 91) and large ADM (>128 cm², n = 206). Demographic, comorbidity, surgical, and outcome data were collected and analyzed. Seroma incidence was assessed by time to drain removal. Results: There was no significant difference in the time to drain removal between cohorts (mean = 13.34 versus 14.09 d). Logistic regression showed a nonsignificant trend toward an increased infection rate in the large ADM cohort (odds ratio = 5.40, Conclusions: Seroma and infection were not significantly influenced by ADM size. These findings suggest that the previously observed increase in these postoperative complications is due to the presence of ADM, rather than its size, supporting the continued efficacy and safety of ADM in prepectoral breast reconstructions.

Identifiers

PMID41244018
PMCPMC12614684

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.