ArticleJournal of inflammation research2025
Relationship Between the Level of CCL13 in Nasal Mucosa Tissue and Postoperative Recurrence in Patients with Chronic Rhinosinusitis.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the relationship between the expression levels of Chemokine C-C Motif Ligand 13 (CCL13) in nasal mucosal tissue and the likelihood of postoperative recurrence in patients with chronic rhinosinusitis (CRS). Patients and Methods: In this retrospective study, we collected clinical data from 230 CRS patients who underwent functional endoscopic sinus surgery at our hospital from January 2022 and December 2023. Based on follow-up results, patients were divided into a recurrence group (66 cases) and a non-recurrence group (164 cases). The concentration of CCL13 in nasal mucosal tissue was measured using ELISA. Statistical analyses were performed using Spearman correlation analysis, multivariate logistic regression analysis, receiver operating characteristic (ROC) curve analysis, and a nomogram model. Results: After a one-year follow-up period, the recurrence rate was 28.70%. The concentration of CCL13 was significantly higher in the recurrence group compared to the non-recurrence group ( Conclusion: The expression level of CCL13 is an independent predictor of postoperative recurrence in CRS and holds significant assessment value. However, this study has some limitations, including its retrospective design and potential selection bias. Future prospective studies are needed to further validate these findings.
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