Evidence map›Paper›PMID 41243690›Full record

Observational studyAnaesthesia2026

Artificial intelligence-assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy.

Alexander Fuchs, Aline Raeber, Ricarda Lippuner, Lea Weber, Yevheniia Borysenko, Markus Huber, Robert Greif, Thomas Riva

Abstract readObservational Study
In one paragraph

Observational study in Anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander FuchsDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.ORCID 0000-0001-7188-1683
Aline RaeberDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.
Ricarda LippunerDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.
Lea WeberDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.
Yevheniia BorysenkoDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.
Markus HuberDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.
Robert GreifMedical Faculty, University of Bern, Bern, Switzerland.ORCID 0000-0003-0160-2073
Thomas RivaDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.ORCID 0000-0003-1297-3427

Funding

Innosuisse - Schweizerische Agentur för Innovationsförderung 56688.1 IP-LS
6 · The paper itself

Abstract

introductionlarynGuide™ is a novel assistive software integrated with the C-MAC

methodsThis prospective, single-centre, investigator-initiated, observational study included adult patients undergoing elective surgery requiring general anaesthesia with tracheal intubation. After informed consent and standardised induction of anaesthesia, laryngoscopy and tracheal intubation were performed with a C-MAC

resultsWe enrolled 132 patients, of whom 110 were analysed. Of 108 patients with correctly placed tracheal tubes, larynGuide identified 102 (sensitivity 0.94, 95%CI 0.88-0.98). In six patients, the software misclassified tracheal tube position: two false negatives (i.e. the software advised a failed tracheal intubation despite correct placement); and four patients with no feedback. Among two patients with unsuccessful tracheal intubation due to oesophageal tube placement at the first attempt, larynGuide detected one. DISCUSSION: This first in-human study has established the feasibility of AI-guided real-time tracheal intubation using larynGuide. The software showed promising sensitivity, while specificity was limited. Videolaryngoscopy image quality issues, including fogging and poor visibility, impaired the performance of the software.

Indexed as

Artificial IntelligenceIntubation, IntratrachealAdultAgedAnesthesia, GeneralCapnographyFemaleHumansLaryngoscopesLaryngoscopyMaleMiddle AgedProspective StudiesReproducibility of ResultsSensitivity and SpecificitySoftwareairway managementartificial intelligencetracheal intubationvideolaryngoscopy

Identifiers

PMID41243690
PMCPMC12893832

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.