Evidence map›Paper›PMID 41243514›Full record

ReviewPathologica2025

Early gestational choriocarcinoma: report of two cases and review of the literature.

Angela Guerriero, Lara Alessandrini, Luisa Santoro, Kathrin Ludwig, Vennus Shafiei, Pietro Goglia, Pava Srsen, Giulia Tasca, Angelo Paolo Dei Tos

Abstract readCase ReportsReviewLetter
PubMed Full text at PMC Publisher
In one paragraph

Review in Pathologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Repurposing metformin for choriocarcinoma: targeting the AMPK/mTOR pathway.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angela GuerrieroSurgical Pathology Unit, Hospital of Padova, Padova, Italy.
Lara AlessandriniSurgical Pathology Unit, Hospital of Padova, Padova, Italy.
Luisa SantoroSurgical Pathology Unit, Hospital of Padova, Padova, Italy.
Kathrin LudwigSurgical Pathology Unit, Hospital of Padova, Padova, Italy.
Vennus ShafieiSurgical Pathology Unit, Hospital of Rovigo, Rovigo, Italy.
Pietro GogliaSurgical Pathology Unit, Hospital of Padova, Padova, Italy.
Pava SrsenSurgical Pathology Unit, Hospital of Padova, Padova, Italy.
Giulia TascaVeneto Institute of Oncology, IOV-IRCCS, Padova, Italy.
Angelo Paolo Dei TosDepartment of Medicine (DIMED), University of Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational choriocarcinoma (GCC) is a malignant and aggressive tumor composed of neoplastic trophoblasts rarely arising months after a normal gestation or after an hydatidiform mole (HM). Histologically, its main diagnostic features are a trimorphic population of trophoblast cells and an absence of chorionic villi. Recently, extremely rare cases of GCC diagnosed in molar and in placenta specimens have been described and accepted as early forms of GCC. We report two cases of GCC diagnosed in a term placenta and in a complete HM (CHM) and underline the importance of recognizing such a rare early form of GCC.

Indexed as

ChoriocarcinomaHydatidiform MoleUterine NeoplasmsFemaleHumansPregnancycomplete hydatidiform molegestational choriocarcinomaintraplacental choriocarcinoma

Identifiers

PMID41243514
PMCPMC12620955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.