Evidence map›Paper›PMID 41243411›Full record

SynthesisPhysiological reports2025

Differences in peak oxygen uptake in heart failure patients with and without cachexia: A systematic review and meta-analysis.

Bharathi Upadhya, Christoforos D Giannaki, Pinelopi S Stavrinou, Julee McDonagh, Mathias Schlögl, Gregory Y H Lip, Konstantinos Prokopidis

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bharathi UpadhyaDivision of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Christoforos D GiannakiDepartment of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Pinelopi S StavrinouDepartment of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Julee McDonaghSchool of Nursing, Faculty of Science, Medicine & Health, The University of Wollongong, Wollongong, New South Wales, Australia.
Mathias SchlöglClinic Barmelweid AG, Barmelweid, Switzerland.
Gregory Y H LipDanish Center for Clinical Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Konstantinos ProkopidisLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.ORCID 0000-0002-6264-9388

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic heart failure (CHF) is characterized by reduced peak oxygen consumption (VO

Indexed as

CachexiaHeart FailureOxygen ConsumptionHumanscachexiaheart failurephysical functionrehabilitationVO2peak

Identifiers

PMID41243411
PMCPMC12620407

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.