Evidence map›Paper›PMID 41243330›Full record

ReviewBritish journal of haematology2026

Damage-associated molecular patterns and coagulation.

Jun Yong, Cheng-Hock Toh

Abstract readReview
In one paragraph

Review in British journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Damage-associated molecular patterns and coagulation.British journal of haematology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jun YongDepartment of Clinical Infection, Microbiology and Immunology, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0002-0092-4604
Cheng-Hock TohDepartment of Clinical Infection, Microbiology and Immunology, University of Liverpool, Liverpool, UK.

Funding

British Heart Foundation PG/14/19/30751British Heart Foundation PG/16/65/32313Department of Health and Social CareLiverpool University Hospitals NHS Foundation TrustNational Institute for Health Research NIHR135073
6 · The paper itself

Abstract

Damage-associated molecular patterns (DAMPs), released into the extracellular space following tissue injury, are increasingly recognised as potent procoagulant molecules integral to haemostasis and the pathogenesis of thrombosis. Their procoagulant influence spans all phases of the cell-based model of coagulation while simultaneously extending beyond traditional haemostatic pathways through direct modulation of inflammatory and innate immune responses. By coupling coagulation and immunity, DAMPs drive the self-perpetuating cycle of immunothrombosis characteristic of many critical illnesses. Targeting this underexplored interface offers the promise of novel diagnostic and therapeutic approaches, particularly in conditions where coagulopathy coexists with hyperinflammatory states.

Indexed as

AlarminsBlood CoagulationAnimalsHemostasisHumansImmunity, InnateThrombosisAlarminscoagulationdamage‐associated molecular patternshistonesinnate immunityneutrophil extracellular trapsthrombin

Identifiers

PMID41243330
PMCPMC12819101

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.