Evidence map›Paper›PMID 41243057›Full record

SynthesisJournal of robotic surgery2025

The Hugo™ RAS system in gynecologic robotic surgery: a systematic review of current applications.

Chiara Innocenzi, Massimo Criscione, Matteo Pavone, Nicolò Bizzarri, Andrea Rosati, Marco Petrillo, Riccardo Oliva, Denis Querleu, Anna Fagotti, Lise Lecointre and 5 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Laparoscopic Versus Robot-Assisted Sacrocolpopexy: A Systematic Review and Meta-Analysis.BJOG : an international journal of obstetrics and gynaecology · 2026
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chiara Innocenzi *UOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Massimo Criscione *UOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Matteo PavoneUOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy. matteopavone.21@gmail.com.
Nicolò BizzarriUOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Andrea RosatiUOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Marco PetrilloDepartment of Medicine, Surgery and Pharmacy, Gynecologic and Obstetric Clinic, University of Sassari, Sassari, Italy.
Riccardo OlivaUOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Denis QuerleuUOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Anna FagottiUOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Lise LecointreInstitute of Image-Guided Surgery, IHU Strasbourg, Strasbourg, France.
Mariano GiménezResearch Institute against Digestive Cancer, IRCAD, Strasbourg, France.
Barbara SeeligerResearch Institute against Digestive Cancer, IRCAD, Strasbourg, France.
Antonello ForgioneResearch Institute against Digestive Cancer, IRCAD, Strasbourg, France.
Francesco FanfaniUOC Ginecologia Oncologica, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Jacques MarescauxResearch Institute against Digestive Cancer, IRCAD, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Hugo™ Robotic-Assisted Surgery (RAS) system is a recent development in minimally invasive gynecologic surgery. Following regulatory approval, its clinical use has expanded. However, comprehensive evidence on feasibility, safety and surgical outcomes has not been established. This systematic review synthesizes the available clinical data on the application of this robotic system across gynecologic procedures. MATERIALS AND

methodsA systematic review was conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD42024519329), interrogating PubMed, Web of Science and Embase databases. Manuscripts reporting data on patients undergoing gynecologic surgical procedures with the Hugo™ RAS platform were included in the analysis.

resultsQualitative analysis was conducted on twelve studies including 445 patients. Hysterectomy was the main procedure (either total or supracervical; n = 289, 64.9%), with primary indications including fibromatosis (n = 149, 33.5%) and endometriosis (n = 92, 20.7%). Some studies (n = 5, 41.7%) included patients with gynecologic malignancies, mainly endometrial cancer; one reported robotic management of a perivesical recurrence. Few conversions (laparotomy n = 1, 0.22%; laparoscopy n = 5, 1.12%), intraoperative complications (n = 4, 0.90%), and postoperative complications (Clavien-Dindo grade ≥ II, 1.57%) occurred. Weighted mean operative, console and docking times were 141.84 ± 28.73, 97.98 ± 28.13, and 5.90 ± 0.94 min, respectively. Estimated blood loss averaged 110.75 ± 84.16 mL, and mean hospital stay was 2 ± 1 days. Reported system malfunctions were generally manageable without significant clinical consequences.

conclusionsCurrent evidence indicates that the system can be safely implemented by gynecologic surgeons in routine clinical practice. Nevertheless, further high-quality research is required to determine long-term outcomes and to assess its integration within the evolving landscape of digital surgical technologies.

Indexed as

Gynecologic Surgical ProceduresRobotic Surgical ProceduresFemaleHumansHysterectomyMinimally Invasive Surgical ProceduresDigital surgeryMinimally invasive surgeryRobotic gynecologic surgerySurgical innovation

Identifiers

PMID41243057
PMCPMC12620324

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.