ArticlePediatric cardiology2026
Fully Automated Evaluation of Left Ventricular Global Longitudinal Strain in Normal Hearts: An Assessment of Accuracy in the Pediatric Population.
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two-dimensional echocardiography has been shown to be a useful modality for analyzing cardiac deformation parameters. However, the clinical utility of strain analysis is limited by time and training required for manual border tracing. This study aims to assess the feasibility of a "hands-off," measurement program, Philips AutoStrain, for measurements of left-ventricular deformation in children. We hypothesize that AutoStrain may accurately calculate deformation measurements, but its performance may be limited in certain patient populations. Echocardiographic images from 168 patients were analyzed via AutoStrain using fully-automated and semiautomated approaches. GLS were manually traced offline as a reference standard. Autostrain outputs were analyzed for accuracy using percent difference from the reference standard and an accuracy scoring system designed to objectively quantify the precision of Autostrain border tracings at the apex and mitral annuli. Both fully-automated and semiautomated AutoStrain correlated well with manual GLS (Fully-automated R = 0.71, Semiautomated R = 0.90). However, the accuracy of AutoStrain was affected by image axis, patient age, and clear visualization of the LV apex. Fully-automated techniques may lead to a "hands-off" future in assessment of LV deformation in older children, but should be used cautiously in younger children until further refinements in the algorithm are performed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.