Evidence map›Paper›PMID 41243017›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

The role of preoperative embolization in carotid body paraganglioma resection: A comparative outcome study.

Mehmet Ekrem Zorlu, Merve Cayir, Fatih Oncu, Muammer Melih Sahin, Suleyman Cebeci, Hakan Tutar, Mehmet Duzlu, Utku Aydil

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehmet Ekrem ZorluDepartment of Otolaryngology and Head & Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey. m_ekrem_zorlu@hotmail.com.ORCID http://orcid.org/0000-0003-0474-8094
Merve CayirDepartment of Otolaryngology and Head & Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0009-0006-0069-469X
Fatih OncuDepartment of Radiology, Gazi University Faculty of Medicine, Ankara, Turkey.ORCID http://orcid.org/0000-0003-1673-7253
Muammer Melih SahinDepartment of Otolaryngology and Head & Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-1804-2730
Suleyman CebeciDepartment of Otolaryngology and Head & Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0003-2302-3371
Hakan TutarDepartment of Otolaryngology and Head & Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-5585-5282
Mehmet DuzluDepartment of Otolaryngology and Head & Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-5641-2915
Utku AydilDepartment of Otolaryngology and Head & Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0003-4076-1798

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the efficacy of preoperative embolization (EMB) and its impact on complication rates in patients undergoing surgery for carotid body tumors (CBT) at a tertiary referral center.

methodsA retrospective analysis was performed on 44 patients who underwent surgical resection of carotid body paragangliomas between January 2000 and June 2024. 13 patients with tumor size less than 3 cm, which is the recommended criterion for preoperative embolization, were excluded from the study. Patients who underwent preoperative embolization (EMB group) were retrospectively compared with patients who did not undergo preoperative embolization (NEMB group). The effects of embolization on cranial nerve injuries, internal carotid artery (ICA) repair, blood loss, operative time, transfusion requirements, and hospital stay duration were evaluated.

resultsPreoperative EMB was not performed in 21 patients (67.7%), and EMB was performed in 10 patients (32.3%) with a CBT > 3 cm. No differences were observed between the two groups in terms of age, gender, tumor size, or Shamblin classification. Additionally, there was no significant difference regarding cranial nerve injury, ICA repair, external carotid artery ligation, or overall complications (p > 0.05). Hemoglobin decrease, operative time, and transfusion requirements were also comparable between the groups (p > 0.05). When the preoperative hospitalization period for embolization was excluded, the mean hospital stay was 4.19 ± 1.37 days in the NEMB group and 4.40 ± 2.46 days in the EMB group with no statistically significant difference (p = 0.761).

conclusionPreoperative EMB did not significantly alter overall complication rates in CBT surgery but may offer particular benefits for large tumors. Given the variability in tumor characteristics among patients, decisions regarding embolization should be individualized.

Indexed as

Carotid Body TumorEmbolization, TherapeuticPreoperative CareAdultAgedBlood Loss, SurgicalCranial Nerve InjuriesFemaleHumansLength of StayMaleMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesTreatment OutcomeCarotid body tumorCranial nerve injuryParagangliomaPreoperative embolization

Identifiers

PMID41243017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.