Evidence map›Paper›PMID 41243016›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Multicenter study results of the med-el partial ossicular replacement prostheses.

Susan Arndt, Christian Offergeld, Wendelin Wolfram, Lisa Niederwanger, Dirk Beutner, Nicholas Bevis, Joachim Hornung, Lava Taha, Piotr H Skarżyński, Łukasz Plichta and 11 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Susan ArndtDepartment of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Medical Center-University of Freiburg, University of Freiburg, 79106, Freiburg, Germany.
Christian OffergeldDepartment of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Medical Center-University of Freiburg, University of Freiburg, 79106, Freiburg, Germany.
Wendelin WolframDepartment of Otorhinolaryngology, Klinikum Wels-Grieskirchen, Wels, 4600, Austria.
Lisa NiederwangerDepartment of Otorhinolaryngology, Klinikum Wels-Grieskirchen, Wels, 4600, Austria.
Dirk BeutnerDepartment of Otolaryngology, University of Goettingen, 37075, Göttingen, Germany.
Nicholas BevisDepartment of Otolaryngology, University of Goettingen, 37075, Göttingen, Germany.
Joachim HornungDepartment of Otorhinolaryngology, Head & Neck Surgery, University of Erlangen- Nuremberg, 91054, Erlangen, Germany.
Lava TahaDepartment of Otorhinolaryngology, Head & Neck Surgery, University of Erlangen- Nuremberg, 91054, Erlangen, Germany.
Piotr H SkarżyńskiCenter of Hearing and Speech MEDINCUS, Clinical Trials Department, Kajetany, Poland.
Łukasz PlichtaCenter of Hearing and Speech MEDINCUS, Clinical Trials Department, Kajetany, Poland.
Thomas LenarzDepartment of Otolaryngology, Hannover Medical School, 30625, Hannover, Germany.
Susan BuschDepartment of Otolaryngology, Hannover Medical School, 30625, Hannover, Germany.
Esther SchimanskiZentrum fuer Mittelohrchirurgie (Centre for Middle Ear Surgery), ENT Practice, Brechtener Straße 59, 44536, Luenen, Germany.
Georg SprinzlDepartment of Otorhinolaryngology, Head & Neck Surgery, University Clinic St. Poelten, St. Pölten, 3100, Austria.
Astrid MageleDepartment of Otorhinolaryngology, Head & Neck Surgery, University Clinic St. Poelten, St. Pölten, 3100, Austria.
Benjamin LoaderDepartment of Otorhinolaryngology, Head and Neck Surgery, 1030 Wiener Gesundheitsverbund, Klinik Landstraße, Vienna, 1030, Austria.
Franz WindischDepartment of Otorhinolaryngology, Head and Neck Surgery, 1030 Wiener Gesundheitsverbund, Klinik Landstraße, Vienna, 1030, Austria.
Nina RubiczDepartment of Otorhinolaryngology, Head and Neck Surgery, Kepler University Hospital GmbH, Krankenhausstrasse 9, Linz, 4020, Austria. nina.rubicz@kepleruniklinikum.at.ORCID http://orcid.org/0000-0001-7740-3623
Paul Martin ZwittagInstitute of Sensory Organs, Kajetany, Poland.
Dominik RissDepartment of Otorhinolaryngology, Medical University of Vienna, Vienna, 1090, Austria.
Christoph ArnoldnerDepartment of Otorhinolaryngology, Medical University of Vienna, Vienna, 1090, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis multicentric, retrospective study aimed to analyze the safety and effectiveness of the mXACT Partial Prosthesis, mXACT PRO Partial Prosthesis, mCLIP Partial Prosthesis, and mCLIP ARC Partial Prosthesis.

methodsPatients underwent partial ossicular replacement with a mXACT Partial Prosthesis, mXACT PRO Partial Prosthesis, mCLIP Partial Prosthesis, or mCLIP ARC Partial Prosthesis (MED-EL). The clinical data was retrospectively analyzed according to the coupling type, bell or clip. Follow-up examination included access to medical records (for adverse events (AE) of the patients, ear microscopy and pure-tone audiometry to determine the post-operative pure tone average of the frequencies 0.5, 1, 2 and 3 kHz (PTA

results203 patients were implanted, 202 patients were examined for AEs (bell group: 68 patients, clip group: 134 patients), 186 patients were examined audiologically (bell group: 63 patients, clip group: 123 patients). In the bell group, 4 patients (5.9%) had 4 AE (thereof 2 revision surgeries and 2 dislocations/extrusions), and in the clip group 15 patients (11.2%) had 28 AEs (thereof 2 revision surgeries and 1 dislocation/extrusion). A post-operative PTA

conclusionClinical data demonstrated satisfactory short-term audiological results after implantation of the mXACT Partial Prosthesis, mXACT PRO Partial Prosthesis, mCLIP Partial Prosthesis, and mCLIP ARC Partial Prosthesis in the majority of patients. The partial ossicular replacement prostheses are safe and effective.

Indexed as

Hearing Loss, ConductiveOssicular ProsthesisOssicular ReplacementAdolescentAdultAgedAudiometry, Pure-ToneBone ConductionChildFemaleFollow-Up StudiesHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesMCLIP ARC partial prosthesisMCLIP partial prosthesisMXACT partial prosthesisMXACT PRO partial prosthesisPartial ossicular replacement prostheses

Identifiers

PMID41243016
PMCPMC13002688

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.