ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Health-related quality of life in cancer survivors aged 65 and older: impact of diagnosis and treatment and perceived decline associated with aging.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Health-Related Quality of Life in Children with Acute Leukaemia and Central Nervous System Tumours: Current Evidence and Future Directions.Children (Basel, Switzerland) · 2026Review
- Health-Related Quality of Life in Lung Cancer Survivors: Sociodemographic, Clinical, and Psychosocial Modulators.Current oncology (Toronto, Ont.) · 2026Article
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4 authors.
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Abstract
purposeThe health-related quality of life (HRQOL) among older adult cancer survivors can be influenced by physiological and psychosocial challenges stemming from treatment and disease experience. Despite assumptions that aging might exacerbate these difficulties, research indicates higher HRQOL in this subgroup compared to younger adult cancer survivors.
objectives(i) to analyze HRQOL in this subgroup, contrasting with younger survivors and (ii) to explore potential moderating factors related to sociodemographic and disease variables.
methodA cross-sectional study was conducted involving 655 Spanish cancer survivors aged 65 or older from several medical centers and cancer patients' associations. HRQOL was assessed using the Quality of Life in Adult Cancer Survivors (QLACS) scale. Participants' data was compared with data from younger survivors (N = 772) [8] . Two Multivariate Variance Analyses (MANOVA) were performed to address the study objectives.
resultsOlder adult survivors exhibited superior HRQOL across all explored domains (except family distress) compared to younger survivors. Predictors of HRQOL included age, primary cancer treatment, and time post-primary treatment. A significant interaction was noted between age and marital status.
conclusionsThe observed higher HRQOL among older adult cancer survivors, particularly in domains seemingly unaffected by cancer, warrants cautious interpretation compared to their younger counterparts. In certain domains, the decline associated with aging might obscure or impede the perception of the true impact of cancer diagnosis and treatment.
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