Evidence map›Paper›PMID 41242971›Full record

ArticleVeterinary ophthalmology2026

The White Coat Effect Influences Intraocular Pressure Measurements in Dogs: Comparing Tonometry Values Obtained in the Clinic Versus Home.

Ruth Pentlarge Barrow, Travis Strong, Kazuya Oikawa, Gillian J McLellan, Ellison Bentley

Abstract readComparative Study
In one paragraph

Article in Veterinary ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruth Pentlarge BarrowDepartment of Surgical Sciences, School of Veterinary Medicine, Madison, Wisconsin (WI), USA.ORCID https://orcid.org/0000-0002-3733-5483
Travis StrongDepartment of Surgical Sciences, School of Veterinary Medicine, Madison, Wisconsin (WI), USA.
Kazuya OikawaDepartment of Surgical Sciences, School of Veterinary Medicine, Madison, Wisconsin (WI), USA.ORCID https://orcid.org/0000-0003-2202-4786
Gillian J McLellanDepartment of Surgical Sciences, School of Veterinary Medicine, Madison, Wisconsin (WI), USA.ORCID https://orcid.org/0000-0002-6505-7476
Ellison BentleyDepartment of Surgical Sciences, School of Veterinary Medicine, Madison, Wisconsin (WI), USA.

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ROBERT W NICKELLS · 2005 to 2026
$12.6M
Structural and Functional Characterization of a Novel Model for Glaucoma ResearchK08EY018609 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI MCLELLAN, GILLIAN JANE · 2008 to 2012
$860k
NEI NIH HHS K08 EY018609NEI NIH HHS P30 EY016665NIH HHS K08EY018609NIH HHS P30EY016665Research to Prevent Blindness
6 · The paper itself

Abstract

objectiveTo determine the effect of clinic versus home environments on intraocular pressure (IOP) measurements in normotensive dogs. ANIMALS: Forty client-owned normotensive dogs.

methodsIn a prospective crossover study, 40 normotensive dogs were included following a complete ophthalmic examination. IOPs were measured in both eyes for each dog using a TonoVet rebound tonometer by a single observer. IOPs were measured in the clinic after the ophthalmic examination, and in the home upon initial entry by the observer (t = 0) and 10 min later (t = 10). Paired t-tests were performed to compare IOP in the clinic versus home and adjusted p < 0.05 followed by the Holm-Šídák correction were considered significant.

resultsMean IOP in the clinic (15.7 mmHg ±2.7) was significantly higher than mean IOP in the home at both t = 0 (14.2 mmHg ±2.2; p < 0.0001) and t = 10 (12.9 mmHg ±1.9; p < 0.0001). Mean IOP in the home at t = 0 (14.2 mmHg ±2.2) was significantly higher than mean IOP in the home at t = 10 (12.9 mmHg ±1.9; p = 0.0001). There was no significant effect of testing site sequence on IOP.

conclusionIOPs measured by tonometry in the clinic are elevated relative to IOPs obtained in the home, by up to 10 mmHg in one eye in this study. Changes in IOP may be rapid, as seen with the significant reduction in IOP over 10 min of acclimation in the home setting. Veterinarians should consider these findings when interpreting IOP values, especially in dogs that are stressed by the clinic environment.

Indexed as

Intraocular PressureTonometry, OcularAnimalsCross-Over StudiesDog DiseasesDogsFemaleMaleProspective Studiescanineglaucomaintraocular pressureocular hypertensiontonometrywhite coat phenomenon

Identifiers

PMID41242971
PMCPMC12867573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.