Evidence map›Paper›PMID 41242959›Full record

ArticleZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2025

[Clinical observation of free rectus femoris flap for repair of surgical defect in pharyngo-laryngeal malignant tumor].

Wen Li, Zhe Chen, Jiayan Wang, Xiaojiao Lan, Zila Pura, Xiaoxing Xiong, Liu Yang

Abstract readEnglish Abstract
In one paragraph

Article in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wen LiDepartment of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.
Zhe ChenDepartment of Stomatology, 66168 Hospital of Chinese PLA, Beijing, 101300, P. R. China.
Jiayan WangDepartment of Otolaryngology Head and Neck Surgery, Ningbo Hospital of Traditional Chinese Medicine, Ningbo Zhejiang, 315010, P. R. China.
Xiaojiao LanDepartment of Otolaryngology Head and Neck Surgery, Fifth People's Hospital of Chengdu, Chengdu Sichuan, 611130, P. R. China.
Zila PuraDepartment of Otolaryngology Head and Neck Surgery, First People's Hospital of Liangshan Yi Autonomous Prefecture, Xichang Sichuan, 615000, P. R. China.
Xiaoxing XiongDepartment of Otolaryngology Head and Neck Surgery, Panzhihua Central Hospital, Panzhihua Sichuan, 617000, P. R. China.
Liu YangDepartment of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the feasibility and effectiveness of repairing surgical defect in pharyngo-laryngeal malignant tumor with free rectus femoris flap. Methods: The clinical data of 34 patients with surgical defects in pharyngo-laryngeal malignant tumor who met the selection criteria between July 2014 and August 2024 were retrospectively analyzed. There were 25 males and 9 females, aged 25-82 years, with a median age of 54 years. The disease duration ranged from 2 months to 2 years, with a median of 7 months. The tumor locations included the oropharynx, hypopharynx, cervical esophagus, and larynx. Pathological types included squamous cell carcinoma (29 cases), myoepithelial carcinoma (2 cases), adenoid cystic carcinoma (1 case), and diffuse large B-cell lymphoma (2 cases). TNM staging: 16 cases of T Results: All the 34 patients were followed up 1-10 years, with an average of 3 years. The flap was found to be necrotic by fibrolaryngoscopy at 1 week after operation in 2 cases, and the incision healed after dressing change and nutritional support, and no reoperation was performed. The flap was in good condition at 1 week after operation in 4 cases, and the signs of gradual necrosis of the flap were found within 1 month after operation, of which 2 cases were healed after dressing change, 1 case was removed the necrotic tissue by reoperation, and 1 case was healed after pectoralis major myocutaneous flap was used to repair the pharyngeal tissue defect. The flaps survived in 28 cases, including 4 cases of pharyngeal fistula, which healed by dressing change. Twenty-two cases achieved satisfactory results in swallowing or phonation. Two patients with total laryngectomy and voice reconstruction underwent reoperation to seal the voice tube because of postoperative aspiration. During the follow-up, 1 case had tracheal stomal recurrence, 2 cases had bone metastasis, and 1 case had bone and lung metastasis. Conclusion: The free rectus femoris flap has good flexibility, the volume of the flap is easy to adjust, and the incision of the donor site is concealed, which is expected to become a new choice for the repair of the surgical defect in pharyngo-laryngeal malignant tumor.

Indexed as

Free Tissue FlapsLaryngeal NeoplasmsPharyngeal NeoplasmsPlastic Surgery ProceduresQuadriceps MuscleSurgical WoundAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomefree flappharyngo-laryngeal tumorRectus femoris musclerepair

Identifiers

PMID41242959
PMCPMC12620290

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