Evidence map›Paper›PMID 41242946›Full record

ArticleZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2025

[Attributable disease burden of low bone mineral density related fractures in people over 50 years old from 1990 to 2023 in China].

Zepeng Lai, Yunxiao Wu, Juxi Jiang, Xiang Shu, Ziqian Zeng, Weizhong Chen

Abstract readEnglish Abstract
In one paragraph

Article in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zepeng LaiSchool of Public Health, Chengdu Medical College, Chengdu Sichuan, 610500, P. R. China.
Yunxiao WuSchool of Public Health, Chengdu Medical College, Chengdu Sichuan, 610500, P. R. China.
Juxi JiangSchool of Public Health, Chengdu Medical College, Chengdu Sichuan, 610500, P. R. China.
Xiang ShuSchool of Public Health, Chengdu Medical College, Chengdu Sichuan, 610500, P. R. China.
Ziqian ZengSchool of Public Health, Chengdu Medical College, Chengdu Sichuan, 610500, P. R. China.
Weizhong ChenSchool of Public Health, Chengdu Medical College, Chengdu Sichuan, 610500, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To estimate the population attributable disease burden (PAD) of low bone mineral density (LBMD) related fractures (fragility fractures) among Chinese people over 50 years old from 1990 to 2023, using data from the Global Burden of Disease Study 2023 (GBD 2023), and to provide evidence for prevention strategies and health resource allocation. Methods: Based on the GBD 2023, the LBMD summary exposure values (SEV), fracture incidence, years lived with disability (YLDs), and LBMD-related falls YLDs of Chinese people over 50 years old from 1990 to 2023 were extracted. PAD was calculated with population attributable fraction (PAF), and an entropy-weight method was applied to evaluate the contribution of individual fracture sites. Temporal trends and sex differences were examined with Joinpoint regression. Results: From 1990 to 2023, the age-standardized SEV of LBMD in people over 50 years old showed an overall decline [average annual percent change (AAPC)=-0.564%]. Age-standardized fracture incidence, fracture YLDs rate, and LBMD-related falls YLDs rate all exhibited W-shaped upward trends (AAPC=1.045%, 0.296%, and 0.724%, respectively). PAF-based estimates indicated that LBMD-attributable fracture incidence likewise increased in a "W-shaped" manner (AAPC=0.558%), whereas the corresponding YLDs rate showed an overall W-shaped decline (AAPC=-0.193%). In international comparison, China and the global average displayed broadly concordant directions of change, with greater volatility in China and a progressive narrowing of the gap after 2015. Regarding sex differences, fracture YLDs rates were consistently higher in the males, whereas the other burden indicators were higher in the females; the temporal patterns were similar in both sexes. Entropy weight method identified hip fractures as contributing most to incidence (weight 0.133), and pelvic fractures as the largest contributor to YLDs rate (weight 0.115). Conclusion: Since 1990, the LBMD attributable fracture burden in China's older population has risen, with female and hip or pelvic fractures bearing the heaviest load. Strengthened osteoporosis screening, improved insurance coverage, and targeted health education are urgently needed to curb further increases in disease burden.

Indexed as

Bone DensityCost of IllnessFractures, BoneOsteoporosisOsteoporotic FracturesAccidental FallsAgedAged, 80 and overChinaDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseHumansIncidenceMaleMiddle Ageddisease burdenfallFracturefragility fracturelow bone mineral densitythe elderlytrend analysis

Identifiers

PMID41242946
PMCPMC12620293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.